A simple approach to assess the cancer risk of occupational exposure to genotoxic drugs in healthcare settings

Autor: Johannes Gerding, Lea Anhäuser, Udo Eickmann, Albert Nienhaus

Publikováno v: Journal of Occupational Medicine and Toxicology, Vol 17, Iss 1, Pp 1-9 (2022)

Abstract Background Several drugs for human use possess genotoxic properties as a necessary consequence of their intended therapeutic effect (e.g. antineoplastics). Health workers may be exposed to these chemicals in various occupational settings suc

Externí odkaz: https://doaj.org/article/07b50723b75f45848d7d0c38825326ef

Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals

Autor: Juana Pincheira, Consuelo de la Torre, Natalie Rodríguez, Carlos Y Valenzuela

Publikováno v: Biological Research, Vol 45, Iss 2, Pp 177-182 (2012)

We analyzed the in vitro effects of the anti-tumoral drugs doxorubicin, cytosine arabinoside and hydroxyurea on the G2-prophase checkpoint in lymphocytes from healthy individuals. At biologically equivalent concentrations, the induced DNA damage acti

Externí odkaz: https://doaj.org/article/fc31eab1890c444985edce3c578998d4

Dynamic reorganization of the cytoskeleton during apoptosis: The two coffins hypothesis

Autor: Mónica Álvarez-Córdoba, Manuel Oropesa-Ávila, José Antonio Sánchez-Alcázar, Patricia de la Cruz-Ojeda, Patricia Ybot-Gonzalez, Irene Villalón-García, Marina Villanueva-Paz, Mario de la Mata, Juan M. Suárez-Rivero, Suleva Povea-Cabello, David Cotán

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2393 (2017)
International Journal of Molecular Sciences

This article belongs to the Special Issue Chemically-Induced DNA Damage, Mutagenesis, and Cancer.
During apoptosis, cells undergo characteristic morphological changes in which the cytoskeleton plays an active role. The cytoskeleton rearrangement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5a1de3ce694f79776b4ea00a5bad91
http://hdl.handle.net/10261/163493

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

Autor: Povea-Cabello, Suleva, Oropesa-Avila, Manuel, de la Cruz-Ojeda, Patricia, Villanueva-Paz, Marina, de la Mata, Mario, Miguel Suarez-Rivero, Juan, Alvarez-Cordoba, Monica, Villalon-Garcia, Irene, Cotan, David, Ybot-Gonzalez, Patricia, Sanchez-Alcazar, Jose A.

During apoptosis, cells undergo characteristic morphological changes in which the cytoskeleton plays an active role. The cytoskeleton rearrangements have been mainly attributed to actinomyosin ring contraction, while microtubule and intermediate fila

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2636::6a05435d84c53347674bc1b6fb7364e4
https://www.mdpi.com/1422-0067/18/11/2393/pdf?version=1510536194

Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals

Autor: J. Pincheira, Consuelo de la Torre, Natalie Rodríguez, Carlos Y Valenzuela

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Biological Research, Vol 45, Iss 2, Pp 177-182 (2012)
Biological Research v.45 n.2 2012
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Volume: 45, Issue: 2, Pages: 177-182, Published: 2012

6 p.-1 tab.
We analyzed the in vitro eff ects of the anti-tumoral drugs doxorubicin, cytosine arabinoside and hydroxyurea on the G2-prophase checkpoint in lymphocytes from healthy individuals. At biologically equivalent concentrations, the induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4353d98ed03b2e376a988b7284e206fd
https://pubmed.ncbi.nlm.nih.gov/23096362