Zobrazeno 1 - 10
of 331
pro vyhledávání: '"genomic heterogeneity"'
Autor:
Hanseol Kim, Kihyun Lee, Ji Young Lee, Bo Eun Kwon, Hyun Jeong Kim, Hyunkyung Park, Taekyung Kim, Jun-Gu Kwak, Joung Eun Choi, Kwang Hee Hong, Jongsik Chun, Changsik Shin
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
IntroductionCutibacterium acnes (C. acnes) resides in various organs such as the skin, prostate, eye, nose, stomach, and intestine, indicating the possibility of extensive crosstalk between this bacterium and the human body. C. acnes strains are clas
Externí odkaz:
https://doaj.org/article/b6f49da66f8845ffb4d0ae5e47a4524c
Autor:
Vishnu Priya Veeraraghavan, Bharati R. Doni, Arun Kumar Dasari, Chaitra Patil, Krishna A. Rao, Santosh R. Patil
Publikováno v:
Oral Oncology Reports, Vol 10, Iss , Pp 100469- (2024)
Oral squamous cell carcinoma (OSCC), which is characterized by high rates of recurrence and metastasis, is a prevalent and burdensome form of head and neck cancer. Genomic heterogeneity and clonal evolution play critical roles in OSCC progression and
Externí odkaz:
https://doaj.org/article/0539489b4925477bbaba19f50f0c5bf4
Autor:
Boyu Zhang, Yajuan Hao, Haiyan Liu, Jiarun Wu, Lu Lu, Xinfeng Wang, Akhilesh K. Bajpai, Xi Yang
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2211 (2024)
Background: N6-methyladenosine (m6A), is the most common modification found in mRNA and lncRNA in higher organisms and plays an important role in physiology and pathology. However, its role in pan-cancer has not been explored. Results: A total of 31
Externí odkaz:
https://doaj.org/article/b33c557e56f3474491e97bdd8bdeaa80
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21174- (2023)
Background: Prostate cancer (PCa) ranks as the second most prevalent malignancy among males on a global scale. Accumulating evidence suggests that inflammation has an intricate relationship with tumorigenesis, tumor progression and tumor immune micro
Externí odkaz:
https://doaj.org/article/2c8d44d202d4491993d9adb9dcf7b254
Autor:
Linlin Zhang, Miaomiao Xu, Wanchun Zhang, Chuanying Zhu, Zhilei Cui, Hongliang Fu, Yufei Ma, Shuo Huang, Jian Cui, Sheng Liang, Lei Huang, Hui Wang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-23 (2023)
Abstract Background Spatial chromatin structure is intricately linked with somatic aberrations, and somatic mutations of various cancer-related genes, termed co-mutations (CoMuts), occur in certain patterns during cancer initiation and progression. T
Externí odkaz:
https://doaj.org/article/c8c3c14b39974997b88ae9309c4103b3
Akademický článek
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Akademický článek
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Autor:
Weian Zhu, Jianjie Wu, Jiongduan Huang, Dongming Xiao, Fengao Li, Chenglun Wu, Xiaojuan Li, Hengda Zeng, Jiayu Zheng, Wenjie Lai, Xingqiao Wen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMacrophages are components of the innate immune system and can play an anti-tumor or pro-tumor role in the tumor microenvironment owing to their high heterogeneity and plasticity. Meanwhile, prostate cancer (PCa) is an immune-sensitive tu
Externí odkaz:
https://doaj.org/article/70eff9e9a74c446c93174b4c2b526922
Akademický článek
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Autor:
Hai‐Ming Huang, Hai‐Xia Li
Publikováno v:
Cancer Communications, Vol 41, Iss 2, Pp 91-108 (2021)
Abstract Bladder cancer (BC) is a heterogeneous disease that characterized by genomic instability and a high mutation rate. Heterogeneity in tumor may partially explain the diversity of responses to targeted therapies and the various clinical outcome
Externí odkaz:
https://doaj.org/article/69bec8dcb14f45e8a995d57bd05261f6