Zobrazeno 1 - 10
of 1 278
pro vyhledávání: '"genomic alterations"'
Autor:
Ji Yoon Lee, Ji Won Lee, Min Sung Chung, Jong Gwon Choi, Sung Hoon Sim, Hyo Jeong Kim, Jeong Eun Kim, Kyoung Eun Lee, Yeon Hee Park, Myoung Joo Kang, Mi Sun Ahn, Yee Soo Chae, Ji Hyun Park, Jee Hyun Kim, Gun Min Kim, Jae Ho Byun, Keon Uk Park, Ju Won Kim, Seung Pil Jung, Jung Hyun Lee, Jung Seok An, Byunghyun Jang, Dayoung Yoon, Jiwon Kim, Jisoo Hong, Harim Koo, Kyu Ran Cho, Cheol Yong Kim, Jason K. Sa, Kyong Hwa Park
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Breast cancer (BC) is a complex disease with profound genomic aberrations. However, the underlying molecular disparity influenced by age and ethnicity remains elusive. Methods In this study, we aimed to investigate the molecular p
Externí odkaz:
https://doaj.org/article/e12f5b2786b14d5bbe27163e1eb5a3d5
Publikováno v:
Cancer Medicine, Vol 13, Iss 22, Pp n/a-n/a (2024)
ABSTRACT Background Triple‐negative breast cancer (TNBC) is a heterogeneous disease characterized by high aggressiveness, high malignancy, and poor prognosis compared to other breast cancer subtypes. Objective This review aims to explore recent adv
Externí odkaz:
https://doaj.org/article/f8a12f6d06bc44c69d4b36a92cb52f34
Autor:
Emmanuella Amoako, Setor Amuzu, Emmanuel Owusu Ofori, Harry Sefoga Akligoh, Randy Tackie, Barikisu Anna Ibrahim, Emmanuel Kofi Quaye, Patrick Kafui Akakpo, Luke Adagrah Aniakwo, Bashiro Jimah, Kofi Ulzen-Appiah, David Hutchful, Aida Manu, Joyce M Ngoi, Lily Paemka, Yakubu Alhassan, Ernest Amo Obeng, Nicole Lim, Lisa Rajah, Michelle Pek, Jack Challis, Ganiyu Adebisi Rahman, Min-Han Tan, Yaw Bediako
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102100- (2024)
Purpose: Breast cancer is a major cause of cancer-related mortality among African women. The adoption of molecular genomic technologies in the management of cancer cases is limited in Africa. To provide much-needed insights on the feasibility and uti
Externí odkaz:
https://doaj.org/article/6c9ad930e71b4823ac09b9f9e44f04a4
Autor:
Gonzalo Ruiz, Diego Enrico, Yamil D. Mahmoud, Alan Ruiz, María Florencia Cantarella, Laura Leguina, Mariana Barberis, Asunción Beña, Esteban Brest, Solange Starapoli, Andrea Mendoza Bertelli, Florencia Tsou, Carmen Pupareli, María Pía Coppola, Alejandra Scocimarro, Susana Sena, Patricio Levit, Aldo Perfetti, Enrique Aman, María Romina Girotti, Oscar Arrieta, Claudio Martín, Rubén Salanova
Publikováno v:
Thoracic Cancer, Vol 15, Iss 11, Pp 895-905 (2024)
Abstract Background Programmed death ligand‐1 (PD‐L1) expression is a well‐known predictive biomarker of response to immune checkpoint blockade in non‐small cell lung cancer (NSCLC). However, there is limited evidence of the relationship betw
Externí odkaz:
https://doaj.org/article/35b2c471fd2f4394a99e4501ff344c9d
Autor:
Anjali Murali, Anju Farsana A, Sobha Subramaniam, Malini Eapen, Indu R. Nair, Keechilat Pavithran
Publikováno v:
Respirology Case Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract Non‐small‐cell lung cancer (NSCLC) accounts for the majority of lung cancer cases worldwide, with a significant proportion of patients harbouring actionable oncogenic alterations. Among these alterations, the ROS1 rearrangement represent
Externí odkaz:
https://doaj.org/article/e576f169d0914bc996d0df38edd7efcd
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionIn this study, we aimed to explore the relationship between clinicopathological features and driver gene changes in Chinese NSCLC patients.MethodsAmplification refractory mutation system PCR was used to detect the aberrations of 10 driver
Externí odkaz:
https://doaj.org/article/696e16fd588a4fd1baa091a999282c5f
Autor:
Carlos A. Ruiz-Perez, Prachi Nakashe, Maggie A. Marshall, Francesco Marass, Tuong Tang, Lisa M. McLennan, Marissa Kroll, Brian K. Flesner, Suzanne Gray, Jill M. Rafalko, Daniel S. Grosu, Susan C. Hicks, John A. Tynan, Dana W.Y. Tsui, Andi Flory, Kristina M. Kruglyak
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
This proof-of-concept evaluation demonstrates that next-generation sequencing-based liquid biopsy can detect genomic alterations in the blood of cats with cancer and the absence of such alterations in the blood of presumably cancer-free cats. Two cat
Externí odkaz:
https://doaj.org/article/574a27c2e3a84f46ba3a5b5f33382d63
Autor:
Gabriela Echeverría-Garcés, María José Ramos-Medina, Rodrigo Vargas, Alejandro Cabrera-Andrade, Adriana Altamirano-Colina, María Paula Freire, Juliana Montalvo-Guerrero, Sebastián Rivera-Orellana, Paulina Echeverría-Espinoza, Luis A. Quiñones, Andrés López-Cortés
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Gastric cancer is one of the most prevalent types of cancer worldwide. The World Health Organization (WHO), the International Agency for Research on Cancer (IARC), and the Global Cancer Statistics (GLOBOCAN) reported an age standardized
Externí odkaz:
https://doaj.org/article/4fc8564a1a65463ea7ee156e96e53092
Autor:
Veronica Zelli, Andrea Manno, Chiara Compagnoni, Rasheed Oyewole Ibraheem, Francesca Zazzeroni, Edoardo Alesse, Fabrizio Rossi, Claudio Arbib, Alessandra Tessitore
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Machine learning (ML) represents a powerful tool to capture relationships between molecular alterations and cancer types and to extract biological information. Here, we developed a plain ML model aimed at distinguishing cancer typ
Externí odkaz:
https://doaj.org/article/288ef954cc5d4dd28645dbf634c63cbe
Publikováno v:
Medicina, Vol 60, Iss 7, p 1173 (2024)
Background and Objectives: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous malignancy influenced by various genetic and environmental factors. Mast cells (MCs), typically associated with allergic responses, have recently emerged as k
Externí odkaz:
https://doaj.org/article/1571a2f5a39647fb8517d31402c67377