Functionality of IAV packaging signals depends on site-specific charges within the viral nucleoprotein.

Autor: Ciminski K; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Flore V; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Jakob C; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Mues H; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Smedegaard Frederiksen A; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schwemmle M; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Bolte H; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Giese S; Institute of Virology, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Publikováno v: Journal of virology [J Virol] 2024 Apr 16; Vol. 98 (4), pp. e0197223. Date of Electronic Publication: 2024 Mar 12.

RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.

Autor: Xia X; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA., Sung PY; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Martynowycz MW; Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA., Gonen T; Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA., Roy P; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Zhou ZH; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: hong.zhou@ucla.edu.

Publikováno v: Cell [Cell] 2024 Apr 25; Vol. 187 (9), pp. 2236-2249.e17. Date of Electronic Publication: 2024 Apr 12.

Biophysical and structural characterization of a multifunctional viral genome packaging motor.

Autor: Prokhorov NS; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA., Davis CR; Program in Structural Biology and Biochemistry, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Maruthi K; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA., Yang Q; Department of Pharmaceutical Chemistry, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Campus, Aurora, CO 80045, USA., Sherman MB; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA., Woodson M; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA., White MA; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA., Miller LM; Department of Chemistry, Indiana University, Bloomington, IN 47405, USA., Jarrold MF; Department of Chemistry, Indiana University, Bloomington, IN 47405, USA., Catalano CE; Program in Structural Biology and Biochemistry, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Pharmaceutical Chemistry, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Campus, Aurora, CO 80045, USA., Morais MC; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Sealy Center for Structural Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Jan 25; Vol. 52 (2), pp. 831-843.

Giant variations in giant virus genome packaging.

Autor: Talbert PB; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: ptalbert@fredhutch.org., Henikoff S; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Armache KJ; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA.

Publikováno v: Trends in biochemical sciences [Trends Biochem Sci] 2023 Dec; Vol. 48 (12), pp. 1071-1082. Date of Electronic Publication: 2023 Sep 28.

Visualizing Viral RNA Packaging Signals in Action.

Autor: Wroblewski E; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Patel N; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom. Electronic address: fbsnpat@leeds.ac.uk., Javed A; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Mata CP; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Chandler-Bostock R; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Lekshmi BG; York Centre for Complex Systems Analysis, University of York, YO10 5DD, United Kingdom; Departments of Mathematics and Biology, University of York, YO10 5DD, United Kingdom., Ulamec SM; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Clark S; York Centre for Complex Systems Analysis, University of York, YO10 5DD, United Kingdom; Departments of Mathematics and Biology, University of York, YO10 5DD, United Kingdom., Phillips SEV; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Ranson NA; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom., Twarock R; York Centre for Complex Systems Analysis, University of York, YO10 5DD, United Kingdom; Departments of Mathematics and Biology, University of York, YO10 5DD, United Kingdom. Electronic address: reidun.twarock@york.ac.uk., Stockley PG; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom. Electronic address: p.g.stockley@leeds.ac.uk.

Publikováno v: Journal of molecular biology [J Mol Biol] 2024 Nov 15; Vol. 436 (22), pp. 168765. Date of Electronic Publication: 2024 Aug 29.