Zobrazeno 1 - 10
of 38
pro vyhledávání: '"genome editing efficiency"'
Autor:
Linli Wang, Hongbing Han
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38588- (2024)
Since its advent, gene-editing technology has been widely used in microorganisms, animals, plants, and other species. This technology shows remarkable application prospects, giving rise to a new biotechnological industry. In particular, third-generat
Externí odkaz:
https://doaj.org/article/2c424e347a1a47ccb8a494966320c9f7
Autor:
Wang, Linli a, b, c, Han, Hongbing a, b, c, ⁎
Publikováno v:
In Heliyon 15 October 2024 10(19)
Akademický článek
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Publikováno v:
PeerJ, Vol 11, p e15771 (2023)
CRISPR/Cas9-mediated genome editing technology has been widely used for the study of gene function in crops, but the differences between species have led to widely varying genome editing efficiencies. The present study utilized a potato hairy root ge
Externí odkaz:
https://doaj.org/article/f7730e115ac84c099077163f04a79651
Autor:
Hiromi Miura, Jurai Imafuku, Aki Kurosaki, Masahiro Sato, Yongjie Ma, Guisheng Zhang, Akiko Mizutani, Kenya Kamimura, Channabasavaiah B. Gurumurthy, Dexi Liu, Masato Ohtsuka
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 325-336 (2021)
The clustered regularly interspersed palindromic repeats (CRISPR) system is a powerful genome-editing tool to modify genomes, virtually in any species. The CRISPR tool has now been utilized in many areas of medical research, including gene therapy. A
Externí odkaz:
https://doaj.org/article/b2c4a229d8a34972a764a0e829f24799
Autor:
Lucia Mattiello, Mark Rütgers, Maria Fernanda Sua-Rojas, Rafael Tavares, José Sérgio Soares, Kevin Begcy, Marcelo Menossi
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
The prokaryote-derived Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas mediated gene editing tools have revolutionized our ability to precisely manipulate specific genome sequences in plants and animals. The simplicity, precision, af
Externí odkaz:
https://doaj.org/article/c1e95a8561734872b6a3e5a85b29e8e9
Autor:
Nasir Javaid, Sangdun Choi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The diverse applications of genetically modified cells and organisms require more precise and efficient genome-editing tool such as clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas). The CRISPR/Cas syste
Externí odkaz:
https://doaj.org/article/1e816245f1ed4f54ad63bf708076edde
Autor:
Xuelian Zheng, Caiyan Qi, Lijia Yang, Quan Quan, Binglin Liu, Zhaohui Zhong, Xu Tang, Tingting Fan, Jianping Zhou, Yong Zhang
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Genome editing technology represented by CRISPR-Cas9 had been widely used in many biological fields such as gene function analysis, gene therapy, and crop improvement. However, in the face of the complexity of the eukaryotic genome, the CRISPR-Cas9 g
Externí odkaz:
https://doaj.org/article/baed03a10a1747c9a679ac49df1ec74d
Akademický článek
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Autor:
Su Ji Ju, Myoung Hui Lee, Eun Yee Jie, Seung Hee Choi, Cha Young Kim, Ji Min Lee, Jiyoung Lee, Suk Weon Kim, Woo Seok Ahn, Da Mon Jin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7817, p 7817 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7817, p 7817 (2021)
Volume 22
Issue 15
Trichostatin A (TSA) is a representative histone deacetylase (HDAC) inhibitor that modulates epigenetic gene expression by regulation of chromatin remodeling in cells. To investigate whether the regulation of chromatin de-condensation by TSA can affe