Zobrazeno 1 - 10
of 1 409
pro vyhledávání: '"genome architecture"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 4027-4035 (2024)
Single-cell Hi-C (scHi-C) techniques have significantly advanced our understanding of the 3D genome organization, providing crucial insights into the spatial genome architecture within individual nuclei. Numerous computational and statistical methods
Externí odkaz:
https://doaj.org/article/2423da2a645a46f5a14566a0a8686b4d
Autor:
Lucas Eduardo Costa Canesin, Sibelle T. Vilaça, Renato R. M. Oliveira, Farooq Al-Ajli, Alan Tracey, Ying Sims, Giulio Formenti, Olivier Fedrigo, Aureo Banhos, Tania M. Sanaiotti, Izeni P. Farias, Erich D. Jarvis, Guilherme Oliveira, Tomas Hrbek, Vera Solferini, Alexandre Aleixo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The Harpy Eagle (Harpia harpyja) is an iconic species that inhabits forested landscapes in Neotropical regions, with decreasing population trends mainly due to habitat loss, and currently classified as vulnerable. Here, we report on a chromo
Externí odkaz:
https://doaj.org/article/c6a4988d919b45cf8fe303fe663d9f6b
Autor:
Julie R. Korenberg
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100270- (2024)
Is the oxytocin-vasopressin (OT-AVP) system a part of the unseen force that subtly (in a clever and indirect way) directs our human fascination to ourselves? And is it possible that this fundamental drive is the inevitable handmaiden of the genetic s
Externí odkaz:
https://doaj.org/article/573a1bddb68544db8e1761ff3cbb341d
Autor:
Aura Stephenson-Gussinye, Luis A. Rendón-Bautista, Blanca E. Ruiz-Medina, Eduardo Blanco-Olais, Rosario Pérez-Molina, Cleofas Marcial-Medina, Yanin Chavarri-Guerra, Enrique Soto-Pérez-de-Celis, Andrea Morales-Alfaro, Ayerim Esquivel-López, Fernando Candanedo-González, Armando Gamboa-Domínguez, Rubén Cortes-González, Alejandro Alfaro-Goldaracena, Sara E. Vázquez-Manjarrez, Guido Grajales-Figueroa, Beatriz Astudillo-Romero, Jesús Ruiz-Manriquez, A. César Poot-Hernández, Paula Licona-Limón, Mayra Furlan-Magaril
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Molecular and cellular characterization of tumors is essential due to the complex and heterogeneous nature of cancer. In recent decades, many bioinformatic tools and experimental techniques have been developed to achieve personalized characterization
Externí odkaz:
https://doaj.org/article/331fba8ae42c45d880cce5649e067768
Autor:
Arpit Mishra, Ajay Jajodia, Eryn Weston, Naresh Doni Jayavelu, Mariana Garcia, Daniel Hossack, R. David Hawkins
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type I diabetes is an autoimmune disease mediated by T-cell destruction of β cells in pancreatic islets. Currently, there is no known cure, and treatment consists of daily insulin injections. Genome-wide association studies and twin studies have ind
Externí odkaz:
https://doaj.org/article/289347cc65d04d078c937b222b6228b9
Autor:
Ningjun Duan, Yijia Hua, Xueqi Yan, Yaozhou He, Tianyu Zeng, Jue Gong, Ziyi Fu, Wei Li, Yongmei Yin
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Secondary trastuzumab resistance represents an evolutionary adaptation of HER2‐positive breast cancer during anti‐HER2 treatment. Most current studies have tended to prioritize HER2 and its associated signaling pathways, often overlookin
Externí odkaz:
https://doaj.org/article/e14eb688c2e34550b89313acb25395d1
Autor:
Edouard Tourdot, Stefan Grob
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151344- (2023)
Research on the three-dimensional (3D) structure of the genome and its distribution within the nuclear space has made a big leap in the last two decades. Work in the animal field has led to significant advances in our general understanding on eukaryo
Externí odkaz:
https://doaj.org/article/051459ca9fee44d9a8b5fd92ff77283e
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Erysiphe necator is an obligate fungal pathogen that causes grape powdery mildew, globally the most important disease on grapevines. Previous attempts to obtain a quality genome assembly for this pathogen were hindered by its high repetitive
Externí odkaz:
https://doaj.org/article/1e746af98f1e42cc9a61e81763a817d0
Autor:
Suresh Kumar, Trilochan Mohapatra
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 126 (2024)
Genetic information in eukaryotic organisms is stored, replicated, transcribed, and inherited through the nucleus of a cell. Epigenetic modifications in the genetic material, including DNA methylation, histone modification, changes in non-coding RNA
Externí odkaz:
https://doaj.org/article/1990dc7821e6416cab3b66194b321d20
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