Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure

Autor: Xiyun Jiang, Mila D. Anasanti, Fotios Drenos, Alexandra I. Blakemore, Raha Pazoki

Publikováno v: Healthcare; Volume 10; Issue 7; Pages: 1296

Data Availability Statement: Not applicable. Supplementary Materials: The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/healthcare10071296/s1, Table S1: UK Biobank data fields for blood pressure, physical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7274eee10260c54da21af141e817066d
https://doi.org/10.20944/preprints202205.0385.v1

PKAN neurodegeneration and residual PANK2 activities in patient erythrocytes

Autor: Thomas Klopstock, Boriana Büchner, David M. Baron, Verena Dobretzberger, Ernst W. Müllner, Ulrich Salzer, Kristina Djinović-Carugo, Holger Prokisch, Maike Werning, G. Mlynek

Publikováno v: Ann. Clin. Transl. Neurol. 7, 1340-1351 (2020)
Annals of Clinical and Translational Neurology, Vol 7, Iss 8, Pp 1340-1351 (2020)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology 7(8), 1340-1351 (2020). doi:10.1002/acn3.51127

Objective: Pantothenate kinase 2-associated neurodegeneration (PKAN) is a rare neurodegenerative disease caused by mutations in the pantothenate kinase 2 (PANK2) gene. PKAN is associated with iron deposition in the basal ganglia and, occasionally, wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2261c69e4a4ac285eff87c70eb8e401b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59767

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype

Autor: Bettina Fiege, Rajesh Kumar, Pamela D. Thompson, Rolf Koehler, Martin Stanulla, Amy L. Sherborne, Sally E. Kinsey, Eamonn Sheridan, Thomas W. Mühleisen, Fay J. Hosking, Miguel Inacio da Silva Filho, Eve Roman, Hauke Thomsen, Martin Zimmermann, Richard S. Houlston, Jayaram Vijayakrishnan, Mel Greaves, Markus M. Nöthen, Julie Irving, Lewin Eisele, Kari Hemminki, Per Hoffmann, Gabriele Migliorini, Yussanne Ma, James M. Allan, Martin Schrappe, Tracy Lightfoot, Claus R. Bartram

Publikováno v: Scopus-Elsevier
Blood 122(19), 3298-3307 (2013). doi:10.1182/blood-2013-03-491316

Acute lymphoblastic leukemia (ALL) is the major pediatric cancer diagnosed in economically developed countries with B-cell precursor (BCP)-ALL, accounting for approximately 70% of ALL. Recent genome-wide association studies (GWAS) have provided the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ed359b38c863e038fb044fbd7a8e69
https://www.ncbi.nlm.nih.gov/pubmed/23996088

Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation

Autor: Che A. Stafford, Alicia-Marie Gassauer, Carina C. de Oliveira Mann, Maria C. Tanzer, Evelyn Fessler, Benedikt Wefers, Dennis Nagl, Gunnar Kuut, Karolina Sulek, Catherine Vasilopoulou, Sophia J. Schwojer, Andreas Wiest, Marie K. Pfautsch, Wolfgang Wurst, Monica Yabal, Thomas Fröhlich, Matthias Mann, Nicolas Gisch, Lucas T. Jae, Veit Hornung

Publikováno v: Stafford, C A, Gassauer, A M, de Oliveira Mann, C C, Tanzer, M C, Fessler, E, Wefers, B, Nagl, D, Kuut, G, Sulek, K, Vasilopoulou, C, Schwojer, S J, Wiest, A, Pfautsch, M K, Wurst, W, Yabal, M, Fröhlich, T, Mann, M, Gisch, N, Jae, L T & Hornung, V 2022, ' Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation ', Nature, vol. 609, pp. 590-596 . https://doi.org/10.1038/s41586-022-05125-x
Nature
Nature 609, 590-596 (2022)
Nature 609(7927), 590-596 (2022). doi:10.1038/s41586-022-05125-x

Bacterial cell wall components provide various unique molecular structures that are detected by pattern recognition receptors (PRRs) of the innate immune system as non-self. Most bacterial species form a cell wall that consists of peptidoglycan (PGN)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427ae2b8a3aa52616dbcd0f0760784c2

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