Zobrazeno 1 - 5
of 5
pro vyhledávání: '"genetics [Receptors, GABA]"'
Autor:
Florian Eckenweber, Michael Willem, Simon Lindner, Karin Wind, Barbara von Ungern-Sternberg, Sabina Tahirovic, Tanja Blume, Christian Sacher, Peter Bartenstein, Axel Rominger, Michael Ewers, Gloria Biechele, Leonie Beyer, Jochen Herms, Matthias Brendel, Nicolai Franzmeier, Paul Cumming, Franz-Josef Gildehaus, Benedikt Zott
Publikováno v:
NeuroImage, Vol 230, Iss, Pp 117707-(2021)
Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2021). Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in AppNL-G-F mice. NeuroImage, 230, p. 117707. Elsevier 10.1016/j.neuroimage.2020.117707
NeuroImage 230, 117707-(2021). doi:10.1016/j.neuroimage.2020.117707
Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2021). Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in AppNL-G-F mice. NeuroImage, 230, p. 117707. Elsevier 10.1016/j.neuroimage.2020.117707
NeuroImage 230, 117707-(2021). doi:10.1016/j.neuroimage.2020.117707
Background In Alzheimer`s disease (AD), regional heterogeneity of β-amyloid burden and microglial activation of individual patients is a well-known phenomenon. Recently, we described a high incidence of inter-individual regional heterogeneity in ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35eb65ad65c3291b7844a3892a198a0
https://mediatum.ub.tum.de/1650338
https://mediatum.ub.tum.de/1650338
Publikováno v:
Trends in endocrinology and metabolism 26(7), 349-356 (2015). doi:10.1016/j.tem.2015.04.001
Trends in Endocrinology and Metabolism
Trends in Endocrinology and Metabolism
Research spanning nearly four decades has assigned to the translocator protein (18 kDa) (TSPO) a critical role, among others, in the mitochondrial import of cholesterol, the subsequent steps of (neuro)steroid production, and systemic endocrine regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e932c16cad509725914028374a77cc6
https://doi.org/10.1016/j.tem.2015.04.001
https://doi.org/10.1016/j.tem.2015.04.001
Publikováno v:
Biomolecular NMR assignments 10(1), 79-83 (2016). doi:10.1007/s12104-015-9642-y
Biomolecular NMR Assignments
Biomolecular NMR Assignments
The integral polytopic membrane protein TSPO is the target for numerous endogenous and synthetic ligands. However, the affinity of many ligands is influenced by a common polymorphism in TSPO, in which an alanine at position 147 is replaced by threoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7abc45b88a1e7daab486ef3c46eb8f2
https://pub.dzne.de/record/138447
https://pub.dzne.de/record/138447
Publikováno v:
ChemBioChem
ChemBioChem 16(10), 1483-1489 (2015). doi:10.1002/cbic.201500217
ChemBioChem 16(10), 1483-1489 (2015). doi:10.1002/cbic.201500217
Ligands of the transmembrane protein TSPO are used for imaging of brain inflammation, but a common polymorphism in TSPO complicates their application to humans. Here we determined the three-dimensional structure and side-chain dynamics of the A147T p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd5f13f334b179e76c49c6da4418720
https://pubmed.ncbi.nlm.nih.gov/25974690
https://pubmed.ncbi.nlm.nih.gov/25974690
Publikováno v:
Journal of integrative neuroscience 13(04), 617-631 (2014). doi:10.1142/S0219635214500228
GABA(A) receptors (GABA(A)Rs) are hetero-pentameric chloride channels and the primary sites for fast synaptic inhibition. We have expressed recombinant γ2 and δ subunits of GABA(A)Rs in cultured hippocampal neurons to analyze the membrane targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2a75ec0cf13e2845f40884cb4aeff
https://pub.dzne.de/record/137670
https://pub.dzne.de/record/137670