Zobrazeno 1 - 4
of 4
pro vyhledávání: '"genetics [RNA Precursors]"'
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15261
International journal of molecular sciences 23(23), 15261 (2022). doi:10.3390/ijms232315261
International journal of molecular sciences 23(23), 15261 (2022). doi:10.3390/ijms232315261
Fabry disease (FD) is a rare X-linked disease due to a multiverse of disrupting mutations within the GLA gene encoding lysosomal α-galactosidase A (AGAL). Absent AGAL activity causes the accumulation of complex glycosphingolipids inside of lysosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bac59a12c669c981b180531acf72d8b
https://pubmed.ncbi.nlm.nih.gov/36499585
https://pubmed.ncbi.nlm.nih.gov/36499585
Autor:
Markus Zweckstetter, Piotr Wysoczanski
Publikováno v:
RNA Biology
RNA biology 13(2), 128-133 (2015). doi:10.1080/15476286.2015.1096484
RNA biology 13(2), 128-133 (2015). doi:10.1080/15476286.2015.1096484
One of the great challenges to structural biologists lies in explaining the complexities of the spliceosome - a ribosome-sized molecular machine that is assembled in a step-wise manner and is responsible for pre-mRNA splicing. The spliceosome is both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7375670f58e51a40f22f5a13089e342b
http://europepmc.org/articles/PMC4829318
http://europepmc.org/articles/PMC4829318
Autor:
Cornelius Schneider, Markus C. Wahl, ShengQi Xiang, Francesca Munari, Piotr Wysoczanski, Simon Trowitzsch, Stefan Becker, Reinhard Lührmann, Markus Zweckstetter
Publikováno v:
Nature structural & molecular biology 21(10), 911-918 (2014). doi:10.1038/nsmb.2889
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology
The precursor mRNA (pre-mRNA) retention and splicing (RES) complex is a spliceosomal complex that is present in yeast and humans and is important for RNA splicing and retention of unspliced pre-mRNA. Here, we present the solution NMR structure of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61f8e3ea9d7f6fddf2b986844004bee
http://hdl.handle.net/11562/973689
http://hdl.handle.net/11562/973689
Autor:
Oliver Puk, Thomas Klopstock, Peter H. Seeburg, Thure Adler, Martin Klingenspor, Jan Rozman, Juan Antonio Aguilar-Pimentel, Anja Schrewe, Sabine M. Hölter, Holger Schulz, Martin Mempel, Andreas Zimmer, Irene Esposito, Martin Hrabě de Angelis, Miyoko Higuchi, Lore Becker, Jochen Graw, Beatrix Naton, Wolfgang Hans, Johannes Beckers, Helmut Fuchs, Marion Horsch, Markus Ollert, Lillian Garrett, Wolftgang Wurst, Alexander Götz, Cornelia Prehn, Eckhard Wolf, Dirk H. Busch, Boris Ivandic, Julia Calzada-Wack, Ildiko Racz, Jerzy Adamski, Birgit Rathkolb, Valerie Gailus-Durner
Publikováno v:
The journal of biological chemistry 286(21), 18614-18622 (2011). doi:10.1074/jbc.M110.200881
The Journal of Biological Chemistry
J. Biol. Chem. 286, 18614-18622 (2011)
The Journal of Biological Chemistry
J. Biol. Chem. 286, 18614-18622 (2011)
ADAR2, an RNA editing enzyme that converts specific adenosines to inosines in certain pre-mRNAs, often leading to amino acid substitutions in the encoded proteins, is mainly expressed in brain. Of all ADAR2-mediated edits, a single one in the pre-mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b161c921f0689bb234faea657361bd8