Zobrazeno 1 - 7
of 7
pro vyhledávání: '"genetics [RNA, Untranslated]"'
Autor:
Andre Fischer, Dennis M. Krüger, Sarah Köster, Tea Berulava, Gerrit Brehm, Rezaul Islam, Robert Epple
Publikováno v:
Mol Neurobiol
Molecular neurobiology 58(6), 2940-2953 (2021). doi:10.1007/s12035-021-02296-y
Molecular Neurobiology
Molecular neurobiology 58(6), 2940-2953 (2021). doi:10.1007/s12035-021-02296-y
Molecular Neurobiology
Neurons are highly compartmentalized cells that depend on local protein synthesis. Messenger RNAs (mRNAs) have thus been detected in neuronal dendrites, and more recently in the pre- and postsynaptic compartments as well. Other RNA species such as mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71ab3d3b00a748e0e3acbc531878a2a
https://pubmed.ncbi.nlm.nih.gov/33710584
https://pubmed.ncbi.nlm.nih.gov/33710584
Publikováno v:
Medical hypotheses 109, 59-64 (2017). doi:10.1016/j.mehy.2017.09.011
Traumatizing events are known to have consequences for the victim which may lead to the development of several well-known mental disorders. Recent research has shown that traumatic events may affect not only the victims' lives, but also that of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76678f871266c7f96bd35492520ca3ac
https://doi.org/10.1016/j.mehy.2017.09.011
https://doi.org/10.1016/j.mehy.2017.09.011
Autor:
Cheryl Y. Brown, Timothy Sadlon, Christopher M. Hope, Ying Y. Wong, Soon Wong, Ning Liu, Holly Withers, Katherine Brown, Veronika Bandara, Batjargal Gundsambuu, Stephen Pederson, James Breen, Sarah Anne Robertson, Alistair Forrest, Marc Beyer, Simon Charles Barry
Publikováno v:
Frontiers in immunology 11, 1269 (2020). doi:10.3389/fimmu.2020.01269
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
There has been much interest in the ability of regulatory T cells (Treg) to switch function in vivo, either as a result of genetic risk of disease or in response to environmental and metabolic cues. The relationship between levels of FOXP3 and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eab96624e1ca1e2e04c78f3f2c4031
https://pub.dzne.de/record/154371
https://pub.dzne.de/record/154371
Publikováno v:
Methods 121-122, 55-67 (2017)
Methods 121-122, 55-67 (2017). doi:10.1016/j.ymeth.2017.02.008
Methods 121-122, 55-67 (2017). doi:10.1016/j.ymeth.2017.02.008
The generation of targeted mouse mutants is a key technology for biomedical research. Using the CRISPR/Cas9 system for induction of targeted double-strand breaks, gene editing can be performed in a single step directly in mouse zygotes. This article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2d957046138368c25b3c5ac9dc8f26
https://pubmed.ncbi.nlm.nih.gov/28263886
https://pubmed.ncbi.nlm.nih.gov/28263886
Publikováno v:
International journal of biochemistry & cell biology 54, 331-337 (2014). doi:10.1016/j.biocel.2014.06.014
The mouse and human brain express a large number of noncoding RNAs (ncRNAs). Some of these are known to participate in neural progenitor cell fate determination, cell differentiation, neuronal and synaptic plasticity and transposable elements derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec2fb1aabc8fbc17a52da55a9a1844c
https://pubmed.ncbi.nlm.nih.gov/24993078
https://pubmed.ncbi.nlm.nih.gov/24993078
Publikováno v:
Der Nervenarzt 84(2), 137-142 (2013). doi:10.1007/s00115-012-3637-z
Spinocerebellar ataxias are genetically heterogeneous autosomal dominant ataxia disorders. To date more than 30 different subtypes are known. In Germany particularly SCA1, SCA2, SCA3 and SCA6 are prevalent, as well as the less frequent subtypes SCA5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49939c224f4006d606f1d82d73ee0b08
https://pubmed.ncbi.nlm.nih.gov/23338152
https://pubmed.ncbi.nlm.nih.gov/23338152
Autor:
Stefanie Könen, Daniela Cadinu, Dorthe Matenia, Astrid Sydow, Frank J.A. Dennissen, Maria Joseph, Eva-Maria Mandelkow, Olga Petrova, Katja Hochgräfe
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications 4(1), 17 (2016). doi:10.1186/s40478-016-0281-z
Acta Neuropathologica Communications 4(1), 17 (2016). doi:10.1186/s40478-016-0281-z
Introduction Mutations of Tau are associated with several neurodegenerative disorders. Recently, the Tau mutation A152T was described as a novel risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease. In vitro Tau-A152T show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ceb231bda414c234a95def42e03d87