Zobrazeno 1 - 4
of 4
pro vyhledávání: '"genetics [Neurofilament Proteins]"'
Autor:
Preische, Oliver, Schultz, Stephanie A, Vöglein, Jonathan, Raichle, Marc, Ringman, John, Roh, Jee Hoon, Salloway, Stephen, Schofield, Peter, Shimada, Hiroyuki, Shiroto, Tomoyo, Shoji, Mikio, Sigurdson, Wendy, Sohrabi, Hamid, Levin, Johannes, Sparks, Paige, Suzuki, Kazushi, Swisher, Laura, Taddei, Kevin, Wang, Jen, Wang, Peter, Weiner, Mike, Wolfsberger, Mary, Xiong, Chengjie, Xu, Xiong, Masters, Colin L, Martins, Ralph, Schofield, Peter R, Rossor, Martin N, Graff-Radford, Neill R, Ghetti, Bernardino, Ringman, John M, Apel, Anja, Noble, James M, Chhatwal, Jasmeer, Goate, Alison M, Benzinger, Tammie L S, Morris, John C, Bateman, Randall J, Wang, Guoqiao, Fagan, Anne M, McDade, Eric M, Gordon, Brian A, Kuhle, Jens, Jucker, Mathias, Network, Dominantly Inherited Alzheimer, Allegri, Ricardo, Amtashar, Fatima, Bateman, Randall, Benzinger, Tammie, Berman, Sarah, Bodge, Courtney, Brandon, Susan, Brooks, William, Kaeser, Stephan A, Buck, Jill, Buckles, Virginia, Chea, Sochenda, Chrem, Patricio, Chui, Helena, Cinco, Jake, Clifford, Jack, Cruchaga, Carlos, D'Mello, Mirelle, Barro, Christian, Donahue, Tamara, Douglas, Jane, Edigo, Noelia, Erekin-Taner, Nilufer, Fagan, Anne, Farlow, Marty, Farrar, Angela, Feldman, Howard, Flynn, Gigi, Fox, Nick, Gräber, Susanne, Franklin, Erin, Fujii, Hisako, Gant, Cortaiga, Gardener, Samantha, Goate, Alison, Goldman, Jill, Gordon, Brian, Graff-Radford, Neill, Gray, Julia, Kuder-Buletta, Elke, Gurney, Jenny, Hassenstab, Jason, Hirohara, Mie, Holtzman, David, Hornbeck, Russ, DiBari, Siri Houeland, Ikeuchi, Takeshi, Ikonomovic, Snezana, Jerome, Gina, Karch, Celeste, la Fougère, Christian, Kasuga, Kensaku, Kawarabayashi, Takeshi, Klunk, William, Koeppe, Robert, Lee, Jae-Hong, Marcus, Daniel, Mason, Neal Scott, Masters, Colin, Laske, Christoph, Maue-Dreyfus, Denise, McDade, Eric, Montoya, Lucy, Mori, Hiroshi, Morris, John, Nagamatsu, Akem, Neimeyer, Katie, Noble, James, Norton, Joanne, Perrin, Richard
Publikováno v:
Nature medicine, vol 25, iss 2
Nature medicine 25(2), 277-283 (2019). doi:10.1038/s41591-018-0304-3
Nature medicine 25(2), 277-283 (2019). doi:10.1038/s41591-018-0304-3
Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ultrasensitive immunoassay technol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b9fd3e17c1bfe604aea53e438c63ed
https://doi.org/10.1038/s41591-018-0304-3
https://doi.org/10.1038/s41591-018-0304-3
Autor:
David Mengel, Tze How Mok, Akin Nihat, Wen Liu, Robert A. Rissman, Douglas Galasko, Henrik Zetterberg, Simon Mead, John Collinge, Dominic M. Walsh
Publikováno v:
Cells 10(12), 3514 (2021). doi:10.3390/cells10123514 special issue: "Biomarkers of Alzheimer’s Disease: New Insights"
Cells
Cells; Volume 10; Issue 12; Pages: 3514
Cells, Vol 10, Iss 3514, p 3514 (2021)
Cells
Cells; Volume 10; Issue 12; Pages: 3514
Cells, Vol 10, Iss 3514, p 3514 (2021)
This study investigates the diagnostic and prognostic potential of different forms of tau in biofluids from patients with Creutzfeldt-Jakob disease (CJD). Extracellular tau, which is molecularly heterogeneous, was measured using ultra-sensitive custo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a219f92400312281a1ff784ae8f39b17
https://pub.dzne.de/record/163418
https://pub.dzne.de/record/163418
Autor:
Ludger Schöls, Johannes R. Lemke, Jens Kuhle, Ilona Krey, Christian Barro, Stefanie N. Hayer, Peter Körtvelyessy, Franziska Rössler
Publikováno v:
Neurology 91(16), 755-757 (2018). doi:10.1212/WNL.0000000000006357
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a devastating disease characterized by rapidly progressing motor impairment and dementia with a mean age at onset of 43 years and a mean survival of 7 years.1 It is ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfff65a5391e926d690ae7322a8a1073
https://doi.org/10.1212/wnl.0000000000006357
https://doi.org/10.1212/wnl.0000000000006357
Autor:
Emma L van der Ende, Lieke H Meeter, Jackie M Poos, Jessica L Panman, Lize C Jiskoot, Elise G P Dopper, Janne M Papma, Frank Jan de Jong, Inge M W Verberk, Charlotte Teunissen, Dimitris Rizopoulos, Carolin Heller, Rhian S Convery, Katrina M Moore, Martina Bocchetta, Mollie Neason, David M Cash, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Chris Butler, Simon Ducharme, Alex Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Giovanni B Frisoni, Stefano Cappa, Yolande A L Pijnenburg, Jonathan D Rohrer, John C van Swieten, Martin N. Rossor, Jason D. Warren, Nick C. Fox, Ione O.C. Woollacott, Rachelle Shafei, Caroline Greaves, Rita Guerreiro, Jose Bras, David L. Thomas, Jennifer Nicholas, Simon Mead, Rick van Minkelen, Myriam Barandiaran, Begoña Indakoetxea, Alazne Gabilondo, Mikel Tainta, Maria de Arriba, Ana Gorostidi, Miren Zulaica, Jorge Villanua, Zigor Diaz, Sergi Borrego-Ecija, Jaume Olives, Albert Lladó, Mircea Balasa, Anna Antonell, Nuria Bargallo, Enrico Premi, Maura Cosseddu, Stefano Gazzina, Alessandro Padovani, Roberto Gasparotti, Silvana Archetti, Sandra Black, Sara Mitchell, Ekaterina Rogaeva, Morris Freedman, Ron Keren, David Tang-Wai, Linn Öijerstedt, Christin Andersson, Vesna Jelic, Hakan Thonberg, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Thomas Cope, Carolyn Timberlake, Timothy Rittman, Christen Shoesmith, Robart Bartha, Rosa Rademakers, Carlo Wilke, Hans-Otto Karnath, Benjamin Bender, Rose Bruffaerts, Philip Vandamme, Mathieu Vandenbulcke, Catarina B. Ferreira, Gabriel Miltenberger, Carolina Maruta, Ana Verdelho, Sónia Afonso, Ricardo Taipa, Paola Caroppo, Giuseppe Di Fede, Giorgio Giaccone, Sara Prioni, Veronica Redaelli, Giacomina Rossi, Pietro Tiraboschi, Diana Duro, Maria Rosario Almeida, Miguel Castelo-Branco, Maria João Leitão, Miguel Tabuas-Pereira, Beatriz Santiago, Serge Gauthier, Sonja Schonecker, Elisa Semler, Sarah Anderl-Straub, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Michela Pievani, Gemma Lombardi, Benedetta Nacmias, Camilla Ferrari, Valentina Bessi
Publikováno v:
The lancet / Neurology 18(12), 1103-1111 (2019). doi:10.1016/S1474-4422(19)30354-0
The Lancet Neurology, 18(12), 1103-1111. ELSEVIER SCIENCE INC
The Lancet Neurology, Vol. 18, No 12 (2019) pp. 1103-1111
van der Ende, E L, Meeter, L H, Poos, J M, Panman, J L, Jiskoot, L C, Dopper, E G P, Papma, J M, de Jong, F J, Verberk, I M W, Teunissen, C, Rizopoulos, D, Heller, C, Convery, R S, Moore, K M, Bocchetta, M, Neason, M, Cash, D M, Borroni, B, Galimberti, D, Sanchez-Valle, R, Laforce, R, Moreno, F, Synofzik, M, Graff, C, Masellis, M, Carmela Tartaglia, M, Rowe, J B, Vandenberghe, R, Finger, E, Tagliavini, F, de Mendonça, A, Santana, I, Butler, C, Ducharme, S, Gerhard, A, Danek, A, Levin, J, Otto, M, Frisoni, G B, Cappa, S, Pijnenburg, Y A L, Rohrer, J D, van Swieten, J C & GENetic Frontotemporal dementia Initiative (GENFI) 2019, ' Serum neurofilament light chain in genetic frontotemporal dementia : a longitudinal, multicentre cohort study ', Lancet Neurology, vol. 18, no. 12, pp. 1103-1111 . https://doi.org/10.1016/S1474-4422(19)30354-0
Lancet Neurology, 18(12), 1103-1111. Lancet Publishing Group
The Lancet Neurology, 18(12), 1103-1111. ELSEVIER SCIENCE INC
The Lancet Neurology, Vol. 18, No 12 (2019) pp. 1103-1111
van der Ende, E L, Meeter, L H, Poos, J M, Panman, J L, Jiskoot, L C, Dopper, E G P, Papma, J M, de Jong, F J, Verberk, I M W, Teunissen, C, Rizopoulos, D, Heller, C, Convery, R S, Moore, K M, Bocchetta, M, Neason, M, Cash, D M, Borroni, B, Galimberti, D, Sanchez-Valle, R, Laforce, R, Moreno, F, Synofzik, M, Graff, C, Masellis, M, Carmela Tartaglia, M, Rowe, J B, Vandenberghe, R, Finger, E, Tagliavini, F, de Mendonça, A, Santana, I, Butler, C, Ducharme, S, Gerhard, A, Danek, A, Levin, J, Otto, M, Frisoni, G B, Cappa, S, Pijnenburg, Y A L, Rohrer, J D, van Swieten, J C & GENetic Frontotemporal dementia Initiative (GENFI) 2019, ' Serum neurofilament light chain in genetic frontotemporal dementia : a longitudinal, multicentre cohort study ', Lancet Neurology, vol. 18, no. 12, pp. 1103-1111 . https://doi.org/10.1016/S1474-4422(19)30354-0
Lancet Neurology, 18(12), 1103-1111. Lancet Publishing Group
BACKGROUND: Neurofilament light chain (NfL) is a promising blood biomarker in genetic frontotemporal dementia, with elevated concentrations in symptomatic carriers of mutations in GRN, C9orf72, and MAPT. A better understanding of NfL dynamics is esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4152ad8ad16d91438040d45c33447d2
https://pub.dzne.de/record/141625
https://pub.dzne.de/record/141625