Zobrazeno 1 - 3
of 3
pro vyhledávání: '"genetics [NADH Dehydrogenase]"'
Autor:
Biousse, Valérie, Newman, Nancy J, Esposti, Simona, La Morgia, Chiara, Priglinger, Claudia, Karanja, Rustum, Blouin, Laure, Taiel, Magali, Sahel, José-Alain, Group, LHON Study, Yu-Wai-Man, Patrick, Carelli, Valerio, Moster, Mark L, Vignal-Clermont, Catherine, Klopstock, Thomas, Sadun, Alfredo A, Sergott, Robert C, Hage, Rabih
Publikováno v:
Journal of Neuro-Ophthalmology
Journal of Neuro-Ophthalmology, Lippincott, Williams & Wilkins, 2020, 41 (3), pp.309-315. ⟨10.1097/wno.0000000000001367⟩
Journal of neuro-ophthalmology 41(3), 309-315 (2021). doi:10.1097/WNO.0000000000001367
Journal of Neuro-Ophthalmology, Lippincott, Williams & Wilkins, 2020, 41 (3), pp.309-315. ⟨10.1097/wno.0000000000001367⟩
Journal of neuro-ophthalmology 41(3), 309-315 (2021). doi:10.1097/WNO.0000000000001367
Supplemental Digital Content is Available in the Text.
Background: RESCUE and REVERSE were 2 Phase 3 clinical trials that assessed the efficacy and safety of intravitreal gene therapy with lenadogene nolparvovec (rAAV2/2-ND4) for the treatment o
Background: RESCUE and REVERSE were 2 Phase 3 clinical trials that assessed the efficacy and safety of intravitreal gene therapy with lenadogene nolparvovec (rAAV2/2-ND4) for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f70ac6a14ffd36a34ac106985e191d
http://europepmc.org/articles/PMC8366761
http://europepmc.org/articles/PMC8366761
Autor:
Günther Rudolph, Magali Taiel, Laure Blouin, Nancy J. Newman, Rustum Karanjia, Catherine Vignal-Clermont, Thomas Klopstock, Serge Picaud, Robert C. Sergott, Valérie Biousse, Gerard Smits, Caroline Chevalier, Mark L. Moster, Valerio Carelli, Chiara La Morgia, Alfredo A. Sadun, Harvey Masonson, Patrick Yu-Wai-Man, Barrett Katz, David J. Calkins, Yordak Salermo, Pierre Burguière, José-Alain Sahel
Publikováno v:
Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2020, 12 (573), ⟨10.1126/scitranslmed.aaz7423⟩
Science Translational Medicine, 2020, 12 (573), ⟨10.1126/scitranslmed.aaz7423⟩
Science translational medicine 12(573), eaaz7423 (2020). doi:10.1126/scitranslmed.aaz7423
Science Translational Medicine, American Association for the Advancement of Science, 2020, 12 (573), ⟨10.1126/scitranslmed.aaz7423⟩
Science Translational Medicine, 2020, 12 (573), ⟨10.1126/scitranslmed.aaz7423⟩
Science translational medicine 12(573), eaaz7423 (2020). doi:10.1126/scitranslmed.aaz7423
International audience; REVERSE is a randomized, double-masked, sham-controlled, multicenter, phase 3 clinical trial that evaluated the efficacy of a single intravitreal injection of rAAV2/2-ND4 in subjects with visual loss from Leber hereditary opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8b2819dfe0c1739c28bb816ac645e4
https://hal.sorbonne-universite.fr/hal-03373492/document
https://hal.sorbonne-universite.fr/hal-03373492/document
Autor:
Katrina G. Waymire, Chun Shi Lin, Fred N. Ross-Cisneros, Eric Sung, Grant R. MacGregor, Douglas C. Wallace, Mark S. Sharpley, Alfredo A. Sadun, Valerio Carelli, Billy X. Pan, Daniel W. Gil, Weiwei Fan, Meagan J. McManus, Peter Baciu
An animal model of Leber hereditary optic neuropathy (LHON) was produced by introducing the human optic atrophy mtDNA ND6 P25L mutation into the mouse. Mice with this mutation exhibited reduction in retinal function by elecroretinogram (ERG), age-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e597036b0610929c45a36ecd985c1d77
https://europepmc.org/articles/PMC3523873/
https://europepmc.org/articles/PMC3523873/