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pro vyhledávání: '"genetics [Interferon-gamma]"'
Autor:
Maria-Sophia Vidali, Louis Boon, Aggelos Banos, Aikaterini Termentzi, Triantafyllos Chavakis, Maren Köhne, Panayotis Verginis, Vasiliki Koliaraki, Aikaterini Hatzioannou, Dimitrios T. Boumpas, Constantinos Fedonidis, Marc Beyer, Theodore Sakelaropoulos, Jerome Zoidakis, Ana Henriques, Panagiotis Georgiadis, Aristotelis Tsirigos, Kristian Händler
Publikováno v:
Nature immunology 21(1), 75-85 (2019). doi:10.1038/s41590-019-0555-2
Nature Immunology
Nature Immunology
Regulatory T (Treg) cells accumulate into tumors, hindering the success of cancer immunotherapy. Yet, therapeutic targeting of Treg cells shows limited efficacy or leads to autoimmunity. The molecular mechanisms that guide Treg cell stability in tumo