Zobrazeno 1 - 2
of 2
pro vyhledávání: '"genetics [Electron Transport Chain Complex Proteins]"'
Autor:
Stefano Bartesaghi, Anna Karlsson, Valentina Minieri, Vincenzo Graziano, Melania Capasso, Nick V. Henriquez, Pierluigi Nicotera, Jayeta Saxena, L. Miguel Martins, Paolo Salomoni, Sara Galavotti, Vincenzo De Laurenzi, A Deli, Joanne Betts, Sebastian Brandner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 112(4), 1059-1064 (2015). doi:10.1073/pnas.1413165112
Alterations of mitochondrial metabolism and genomic instability have been implicated in tumorigenesis in multiple tissues. High-grade glioma (HGG), one of the most lethal human neoplasms, displays genetic modifications of Krebs cycle components as we
Autor:
Enrico Glaab, Thomas Ott, Hartwig Wolburg, Stefan Helling, Julia C. Fitzgerald, Rejko Krüger, Caroline May, Jing Chen, Katrin Marcus, Nicolas Casadei, Poonam Sood, Silke Nuber, Olaf Riess, Petra Fallier-Becker, Doron Rapaport, Thomas Ulrich, Nicole Kieper
Publikováno v:
Human molecular genetics 25(24), ddw353 (2016). doi:10.1093/hmg/ddw353
Human molecular genetics 25(3), 459-471 (2015). doi:10.1093/hmg/ddv485
Human Molecular Genetics
Human molecular genetics 25(3), 459-471 (2015). doi:10.1093/hmg/ddv485
Human Molecular Genetics
The protease HtrA2 has a protective role inside mitochondria, but promotes apoptosis under stress. We previously identified the G399S HtrA2 mutation in Parkinson's disease (PD) patients and reported mitochondrial dysfunction in vitro. Mitochondrial d