Zobrazeno 1 - 5
of 5
pro vyhledávání: '"genetics [DNA Repair Enzymes]"'
Autor:
Ricarda Grzybowski, Erik Hanff, Rainer H. Böger, D. Tsikas, Kathrin Cordts, Christian Gerloff, Axel Neu, Ali Sasani, Chi-Un Choe, Dirk Isbrandt, Sönke Hornig, Edzard Schwedhelm
Publikováno v:
Amino acids 52(1), 73-85 (2019). doi:10.1007/s00726-019-02812-4
Statin-induced myopathy affects more than 10 million people worldwide. But discontinuation of statin treatment increases mortality and cardiovascular events. Recently, l-arginine:glycine amidinotransferase (AGAT) gene was associated with statin-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe4cb8e5eadb2c2955bef83ca8dd4f8
Autor:
Radke, Josefine, Koch, Arend, Pritsch, Fabienne, Schumann, Elisa, Misch, Martin, Hempt, Claudia, Lenz, Klaus, Löbel, Franziska, Paschereit, Fabienne, Heppner, Frank L., Vajkoczy, Peter, Koll, Randi, Onken, Julia
Publikováno v:
Acta Neuropathologica Communications 7(1), 89 (2019). doi:10.1186/s40478-019-0745-z
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise predictive cutoff values to distinguish “MGMT methylated” from “MGMT unmethylated” pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d81c40d03e1c6a9208450ced4bbfcc6
Autor:
Felice Giangaspero, Riccardo Maurizi Enrici, Giuseppe Minniti, Gaetano Lanzetta, Domenica Di Stefano, Mattia Falchetto Osti, Andrea Pace, Claudia Scaringi, Stefania Scarpino, Antonella Arcella
Combination of procarbazine, lomustine and vincristine (PCV) with radiation therapy (RT) has been associated with longer survival in patients with anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA), especially in those with chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaf3f5412832e4075005442efe576d8
http://hdl.handle.net/11573/635590
http://hdl.handle.net/11573/635590
Autor:
Silvia Rasi, Elisa Sozzi, Gianluca Gaidano, Francesco Forconi, Davide Rossi, Alessio Bruscaggin
Publikováno v:
Blood. 115(5)
To the editor: Sellick et al[1][1] showed the prognostic role of single nucleotide polymorphisms (SNPs) in chronic lymphocytic leukemia (CLL). The primary end point of the study was progression-free survival (PFS) after first treatment.[1][1] Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e12870817b9f9d8876b1c3a14cb7ff0
https://pubmed.ncbi.nlm.nih.gov/18006695
https://pubmed.ncbi.nlm.nih.gov/18006695
Autor:
Katja Sträßer, Sophia Hartung, Carolin Möckel, Emanuel Clausing, Derk J. Bemeleit, María Lucas, Christian B. Schiller, Alexandra Schele, Karl-Peter Hopfner, Katja Lammens, Christof Angermüller, Johannes Söding
Publikováno v:
Cell
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Summary The MR ( M re11 nuclease and R ad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA double-strand breaks, highly genotoxic lesions linked to cancer development. MR can recognize and process DNA ends even if they are blocked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9c4a2916ab3742bb61701d052675a