Zobrazeno 1 - 5
of 5
pro vyhledávání: '"genetics [Clusterin]"'
Autor:
A. Espinosa, André Lacour, Steffen Wolfsgruber, Isabel Hernández, W. Maier, Octavio Rodriguez-Gomez, J. Kornhuber, Eva Louwersheimer, Mercè Boada, Holger Wagner, SG Riedel-Heller, G. Ortega, Yolande A.L. Pijnenburg, Oscar Sotolongo-Grau, Tim Becker, Teddy Koene, Markus M. Nöthen, Oliver Peters, Susana Ruiz, Henne Holstege, W.M. van der Flier, Sonia Moreno-Grau, Victoria Fernández, Lutz Frölich, Frank Jessen, Agustín Ruiz, Philip Scheltens, Montserrat Alegret, Martin Scherer, Ana Mauleón, Maitée Rosende-Roca, L. Tárraga, Jens Wiltfang, Michael Wagner, E. Rüther, Michael Hüll, Stefanie Heilmann, Alfredo Ramirez, Liliana Vargas
Publikováno v:
Molecular psychiatry 22(1), 153-160 (2016). doi:10.1038/mp.2016.18
Molecular Psychiatry
Molecular Psychiatry, 22(1), 153-160. Nature Publishing Group
Lacour, A, Espinosa, A, Louwersheimer, E, Heilmann, S, Hernández, I, Wolfsgruber, S, Fernández, V, Wagner, H, Rosende-Roca, M, Mauleón, A, Moreno-Grau, S, Vargas, L, Pijnenburg, Y A L, Koene, T, Rodríguez-Gómez, O, Ortega, G, Ruiz, S, Holstege, H, Sotolongo-Grau, O, Kornhuber, J, Peters, O, Frölich, L, Hüll, M, Rüther, E, Wiltfang, J, Scherer, M, Riedel-Heller, S, Alegret, M, Nöthen, M M, Scheltens, P, Wagner, M, Tárraga, L, Jessen, F, Boada, M, Maier, W, Van Der Flier, W M, Becker, T, Ramirez, A & Ruiz, A 2017, ' Genome-wide significant risk factors for Alzheimer's disease : Role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment ', Molecular Psychiatry, vol. 22, no. 1, pp. 153-160 . https://doi.org/10.1038/mp.2016.18
Molecular Psychiatry
Molecular Psychiatry, 22(1), 153-160. Nature Publishing Group
Lacour, A, Espinosa, A, Louwersheimer, E, Heilmann, S, Hernández, I, Wolfsgruber, S, Fernández, V, Wagner, H, Rosende-Roca, M, Mauleón, A, Moreno-Grau, S, Vargas, L, Pijnenburg, Y A L, Koene, T, Rodríguez-Gómez, O, Ortega, G, Ruiz, S, Holstege, H, Sotolongo-Grau, O, Kornhuber, J, Peters, O, Frölich, L, Hüll, M, Rüther, E, Wiltfang, J, Scherer, M, Riedel-Heller, S, Alegret, M, Nöthen, M M, Scheltens, P, Wagner, M, Tárraga, L, Jessen, F, Boada, M, Maier, W, Van Der Flier, W M, Becker, T, Ramirez, A & Ruiz, A 2017, ' Genome-wide significant risk factors for Alzheimer's disease : Role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment ', Molecular Psychiatry, vol. 22, no. 1, pp. 153-160 . https://doi.org/10.1038/mp.2016.18
Few data are available concerning the role of risk markers for Alzheimer's disease (AD) in progression to AD dementia among subjects with mild cognitive impairment (MCI). We therefore investigated the role of well-known AD-associated single-nucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f22b98b57e6b14465c567933aa4c90f
https://pub.dzne.de/record/139044
https://pub.dzne.de/record/139044
Autor:
Markus M. Nöthen, Manuel Mattheisen, Marcella Rietschel, Stephanie H. Witt, Knut Schnell, Sven Cichon, Susanne Erk, Carola Opitz von Boberfeld, Thomas W. Mühleisen, Andreas Meyer-Lindenberg, Christine Esslinger, Henrik Walter, Peter Kirsch
Publikováno v:
The journal of neuroscience 31, 18180-18184 (2011). doi:10.1523/JNEUROSCI.4960-11.2011
Alzheimer's disease is a devastating, common, progressive dementia with considerable heritability. Recently, a genetic variant associated with the disease was discovered atCLU(rs11136000) with genome-wide support. Here we show, using an imaging genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205f819eaa50ed298d730f875a174a0e
https://doi.org/10.1523/jneurosci.4960-11.2011
https://doi.org/10.1523/jneurosci.4960-11.2011
Autor:
Jörg Tatzelt, Mark R. Wilson, Ulrike K. Resenberger, Gerd Multhaup, Veronika Müller, Michael Baier, Konstanze F. Winklhofer, Lisa M. Munter
Publikováno v:
The journal of biological chemistry 287(52), 43765-43776 (2012). doi:10.1074/jbc.M112.389007
The heat shock response (HSR) is an evolutionarily conserved pathway designed to maintain proteostasis and to ameliorate toxic effects of aberrant protein folding. We have studied the modulation of the HSR by the scrapie prion protein (PrP(Sc)) and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093010fe7ace63029c7d46febd325766
https://europepmc.org/articles/PMC3527961/
https://europepmc.org/articles/PMC3527961/
Publikováno v:
The journal of the American Medical Association 305(13), 1322 (2011). doi:10.1001/jama.2011.381
JAMA-Journal of the American Medical Association, 305(13), 1322-1326. American Medical Association
JAMA-Journal of the American Medical Association, 305(13), 1322-1326. American Medical Association
Context Variants in the clusterin gene are associated with the risk of Alzheimer disease (AD) and clusterin levels have been found to be increased in brain and cerebrospinal fluid of patients with AD. Plasma clusterin was reported to be associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056412cf17b42da88b2a23ccee49552c
https://pubmed.ncbi.nlm.nih.gov/22084130
https://pubmed.ncbi.nlm.nih.gov/22084130
Autor:
Horst Bickel, Birgitt Wiese, Michael Pentzek, Wolfgang Maier, Frank Jessen, Julie Williams, Cadja Bachmann, Siegfried Weyerer, Hendrik van den Bussche, Steffi G. Riedel-Heller, Britta Schürmann
Publikováno v:
Journal of Alzheimer's disease 25(3), 421-424 (2011). doi:10.3233/JAD-2011-110251
A variant within the clusterin gene has been recently associated with increased risk for Alzheimer's disease (AD) in genome wide association studies. Here we tested the association of the respective single nucleotide polymorphisms (rs11136000) with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba43cf7441222e12af6ac23ea7330958
https://pubmed.ncbi.nlm.nih.gov/21422520
https://pubmed.ncbi.nlm.nih.gov/21422520