Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

Autor: Thimoteus Speer, Anna Paschen, Joachim Jankowski, David Schmit, Lucia Rohrer, Eicke Latz, Sarah Triem, Willi Jahnen-Dechent, Jochen Reiser, Vera Jankowski, Barbara A. Niemeyer, Gunter Aßmann, Gerhard M. Kostner, Michael D. Menger, Christina Körbel, Danilo Fliser, Stephen Zewinger, Susanne Schuster, Rafael Kramann, Michael Böhm, Simina-Ramona Selejan, Manfred Kopf, Winfried März, Ulrich Laufs, Dalia Alansary, Mira Klug, Eunsil Hahm, Tobias Herter, Günther Silbernagel, Robert Bals, Martina Sester, Urban Sester, Emmanuel Ampofo, Stefan J Schunk, Matthias W. Laschke

Publikováno v: Nature Immunology, 21(1), 30-+. Nature Publishing Group
Nature immunology 21(1), 30-41 (2019). doi:10.1038/s41590-019-0548-1
Nature Immunology, 21(1), 30-41. Nature Publishing Group

NLRP3-inflammasome-driven inflammation is involved in the pathogenesis of a variety of diseases. Identification of endogenous inflammasome activators is essential for the development of new anti-inflammatory treatment strategies. Here, we identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f4f8bbeae748a0cac86e45204497f6
https://cris.maastrichtuniversity.nl/en/publications/ebd63dda-1451-4416-9dff-90b522012719