Zobrazeno 1 - 3
of 3
pro vyhledávání: '"genetics [5' Untranslated Regions]"'
Autor:
Ali Bozorgmehr, Mostafa Tavakoli, Zahra Jafarian, Hossein Afshar, Razieh Moayedi, Maryam Keshavarz, Mina Ohadi, Safoura Khamse
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific reports 11(1), 20629 (2021). doi:10.1038/s41598-021-99932-3
Scientific Reports
Scientific reports 11(1), 20629 (2021). doi:10.1038/s41598-021-99932-3
Scientific Reports
PRKACB (Protein Kinase CAMP-Activated Catalytic Subunit Beta) is predominantly expressed in the brain, and regulation of this gene links to neuroprotective effects against tau and Aβ-induced toxicity. Here we studied a (GCC)-repeat spanning the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32360dac237b0e73b169c40eb7438447
https://doi.org/10.1038/s41598-021-99932-3
https://doi.org/10.1038/s41598-021-99932-3
Publikováno v:
The journal of biological chemistry 289(37), 25879-25889 (2014). doi:10.1074/jbc.M114.560128
Frontotemporal lobar degeneration is associated with cytoplasmic or nuclear deposition of the TAR DNA-binding protein 43 (TDP-43). Haploinsufficiency of progranulin (GRN) is a major genetic risk factor for frontotemporal lobar degeneration associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793e1c84c38ddcab7db0f1a3c2a6f835
https://doi.org/10.1074/jbc.m114.560128
https://doi.org/10.1074/jbc.m114.560128
Autor:
Ronald C. Petersen, William W. Seeley, Glenda M. Halliday, Dennis W. Dickson, Ian R. A. Mackenzie, Manuela Neumann, John C. van Swieten, Rosa Rademakers, Matt Baker, Bradley F. Boeve, Keith A. Josephs, Nicola J. Rutherford, Thomas A. Ravenscroft, Jillian J. Kril
Publikováno v:
Neurobiology of aging 34(9), 2235.e11-2235.e13 (2013). doi:10.1016/j.neurobiolaging.2013.04.004
Neurobiology of Aging, 34(9), 2235.e11-2235.e13. Elsevier Inc.
Neurobiology of Aging
Neurobiology of aging, vol 34, iss 9
Neurobiology of aging
Neurobiology of Aging, 34(9). Elsevier Inc.
Ravenscroft, T A, Baker, M C, Rutherford, N J, Neumann, M, Mackenzie, I R, Josephs, K A, Boeve, B F, Petersen, R, Halliday, G M, Kril, J, van Swieten, J C, Seeley, W W, Dickson, D W & Rademakers, R 2013, ' Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS ', Neurobiology of Aging, vol. 34, no. 9, pp. 2235.e11-2235.e13 . https://doi.org/10.1016/j.neurobiolaging.2013.04.004
Neurobiology of Aging, 34(9), 2235.e11-2235.e13. Elsevier Inc.
Neurobiology of Aging
Neurobiology of aging, vol 34, iss 9
Neurobiology of aging
Neurobiology of Aging, 34(9). Elsevier Inc.
Ravenscroft, T A, Baker, M C, Rutherford, N J, Neumann, M, Mackenzie, I R, Josephs, K A, Boeve, B F, Petersen, R, Halliday, G M, Kril, J, van Swieten, J C, Seeley, W W, Dickson, D W & Rademakers, R 2013, ' Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS ', Neurobiology of Aging, vol. 34, no. 9, pp. 2235.e11-2235.e13 . https://doi.org/10.1016/j.neurobiolaging.2013.04.004
The nuclear protein fused in sarcoma (FUS) is found in cytoplasmic inclusions in a subset of patients with the neurodegenerative disorder frontotemporal lobar degeneration (FTLD-FUS). FUS contains a methylated arginine-glycine-glycine domain that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c684b28f1c3b800e70556709fc2cf2d
