Výsledky vyhledávání - "genetics/metabolism, Chromosome"

The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability

Autor: Laura Ciapponi, Maurizio Gatti, Giovanni Cenci

Publikováno v: Genetics. 173(3)

The Mre11/Rad50/Nbs (MRN) complex and the two protein kinases ATM and ATR play critical roles in the response to DNA damage and telomere maintenance in mammalian systems. It has been previously shown that mutations in the Drosophila mre11 and rad50 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9966c0cbc311aa8cbe7e69de38564f
https://pubmed.ncbi.nlm.nih.gov/16648644

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Thymosin beta-10 gene overexpression correlated with the highly malignant neoplastic phenotype of transformed thyroid cells in vivo and in vitro

Autor: D, Califano, C, Monaco, G, Santelli, A, Giuliano, M L, Veronese, M T, Berlingieri, V, de Franciscis, N, Berger, F, Trapasso, M, Santoro, G, Viglietto, A, Fusco

A subtractive thyroid cDNA library was constructed from two human thyroid carcinoma cell lines originating from an anaplastic carcinoma and a papillary thyroid carcinoma. The library was used to identify genes correlated with the progression to a hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dc7d3030c12983562113df0783459931
http://hdl.handle.net/11588/484009

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In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity

Autor: Bautista, S., Vallès, H., Walker, R. L., Anzick, S., Zeillinger, R., Meltzer, P., Charles Theillet

Publikováno v: Europe PubMed Central
Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 1998, 4 (12), pp.2925--9
Scopus-Elsevier

The AIB1 gene was isolated upon microdissection of the homogeneously staining regions observed in breast cancer cell lines. It was subsequently shown to map at a region at 20q12 that is frequently amplified in breast tumors. In a screen of breast tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fae091b76be4b539c69195ba6586fd2a
http://europepmc.org/abstract/med/9865902

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