Zobrazeno 1 - 10
of 1 483
pro vyhledávání: '"genetic screens"'
Autor:
Zina Alaswad, Nayera E. Attallah, Basma Aboalazm, Eman S. Elmeslhy, Asmaa S. Mekawy, Fatma A. Afify, Hesham K. Mahrous, Ashrakat Abdalla, Mai A. Rahmoon, Ahmed A. Mohamed, Ahmed H. Shata, Rana H. Mansour, Fareed Aboul-ela, Mohamed Elhadidy, Biola M. Javierre, Sherif F. El-Khamisy, Menattallah Elserafy
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 4, Pp 100427- (2024)
The utilization of human cDNA libraries in yeast genetic screens is an approach that has been used to identify novel gene functions and/or genetic and physical interaction partners through forward genetics using yeast two-hybrid (Y2H) and classical c
Externí odkaz:
https://doaj.org/article/85075acebc0142d48692eeb42ddb7a45
Autor:
David W. Vredevoogd, Daniel S. Peeper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Functional genetic screens to uncover tumor-intrinsic nodes of immune resistance have uncovered numerous mechanisms by which tumors evade our immune system. However, due to technical limitations, tumor heterogeneity is imperfectly captured with many
Externí odkaz:
https://doaj.org/article/1d4dfe7156154877945b7c562fca72c3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The brain is arguably the most complex part of the human body in form and function. Much remains unclear about the molecular mechanisms that regulate its normal and pathological physiology. This lack of knowledge largely stems from the inaccessible n
Externí odkaz:
https://doaj.org/article/1551d9cb181d46cc8679977e08f0c7f5
Autor:
Cynthia H. Chiu
Publikováno v:
Current Research in Biotechnology, Vol 5, Iss , Pp 100127- (2023)
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system is a powerful gene editing tool originated from prokaryotes. The modern CRISPR/Cas9 system allows high-throughput genetic screening to be
Externí odkaz:
https://doaj.org/article/8d036eb4908a457e9bf2c17ce938c0bd
Autor:
Nancy M. Bonini
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Drosophila has been long appreciated as a classic genetic system for its ability to define gene function in vivo. Within the last several decades, the fly has also emerged as a premiere system for modeling and defining mechanisms of human disease by
Externí odkaz:
https://doaj.org/article/73543be0c14f4f7cb00b84f40931dd4b
Akademický článek
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Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Forward genetic approaches have been widely used in parasitology and have proven their power to reveal the complexities of host-parasite interactions in an unbiased fashion. Many aspects of the parasite’s biology, including the identification of vi
Externí odkaz:
https://doaj.org/article/a4e92d455d84477e88bce13b47570722
Autor:
Prateek Gupta, Joseph Hirschberg
Publikováno v:
Frontiers in Plant Science, Vol 12 (2022)
Carotenoids comprise the most widely distributed natural pigments. In plants, they play indispensable roles in photosynthesis, furnish colors to flowers and fruit and serve as precursor molecules for the synthesis of apocarotenoids, including aroma a
Externí odkaz:
https://doaj.org/article/9296fdff5aab4fbf887b8da510aa1d4b
Akademický článek
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Akademický článek
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