Tracking genomic cancer evolution for precision medicine: The Lung TRACERx Study

Autor: Salli Muller, Karl S. Peggs, David A. Waller, Elza C de Bruin, Natasha Iles, Magali Taylor, Helen E. Davies, Leena Dennis Joseph, Matthew G Krebs, David Lawrence, Gerald Langman, Maggie Wilcox, Alan Hackshaw, Fiona H Blackhall, Jonathan Bennett, Mairead MacKenzie, Richard Booton, Haydn Adams, Seema Shafi, Daisuke Nonaka, Yenting Ngai, Sam M. Janes, Gary Middleton, Jacqueline A Shaw, Ged Brady, John Le Quesne, Ian Woolhouse, Mariam Jamal-Hanjani, Jason F. Lester, Iftekhar Khan, Tanya Ahmad, Mahendran Chetty, Martin Forster, Richard Mitter, Madhav Djearman, Charles Swanton, Joy Millar, Andrew Rowan, Sean W. Smith, Keith Buchan, A R Denison, Nicolai Juul Birkbak, Nik Matthews, Selvaraju Veeriah, Sergio A. Quezada, Dean A. Fennell, Hardy Remmen, Aengus Stuart, Catrin Pritchard, Nirupa Murugaesu, Malgorzata Kornaszewska, Elaine Smith, Siow Ming Lee, Nicholas McGranahan, Arrigo Capitano, Babu Naidu, Caroline Dive, Marianne Nicolson, Rajesh Shah, Richard Attanoos, Yvonne Summers, Bruno Morgan, Stuart Horswell, Mark Cobbold, Ben Wilcox, Keith M. Kerr, Tom Haswell, Philip A.J. Crosbie, Jacki Goldman, Max Salm, Mary Falzon

Publikováno v: Jamal-Hanjani, M, Hackshaw, A, Ngai, Y, Shaw, J, Dive, C, Quezada, S, Middleton, G, de Bruin, E, Le Quesne, J, Shafi, S, Falzon, M, Horswell, S, Blackhall, F, Khan, I, Janes, S, Nicolson, M, Lawrence, D, Forster, M, Fennell, D, Lee, S-M, Lester, J, Kerr, K, Muller, S, Iles, N, Smith, S, Murugaesu, N, Mitter, R, Salm, M, Stuart, A, Matthews, N, Adams, H, Ahmad, T, Attanoos, R, Bennett, J, Birkbak, N J, Booton, R, Brady, G, Buchan, K, Capitano, A, Chetty, M, Cobbold, M, Crosbie, P, Davies, H, Denison, A, Djearman, M, Goldman, J, Haswell, T, Joseph, L, Kornaszewska, M, Krebs, M, Langman, G, MacKenzie, M, Millar, J, Morgan, B, Naidu, B, Nonaka, D, Peggs, K, Pritchard, C, Remmen, H, Rowan, A, Shah, R, Smith, E, Summers, Y, Taylor, M, Veeriah, S, Waller, D, Wilcox, B, Wilcox, M, Woolhouse, I, McGranahan, N & Swanton, C 2014, ' Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study ', P L o S Biology, vol. 12, no. 7, e1001906 . https://doi.org/10.1371/journal.pbio.1001906
PLoS Biology, Vol 12, Iss 7, p e1001906 (2014)
PLoS Biology

TRACERx, a prospective study of patients with primary non-small cell lung cancer, aims to map the genomic landscape of lung cancer by tracking clonal heterogeneity and tumour evolution from diagnosis to relapse.
The importance of intratumour gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78f6cf4fa6457fa6bd2f2cbcde6710c
https://eprints.gla.ac.uk/217813/2/217813.PDF