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Balancing the transcriptome: leveraging sample similarity to improve measures of gene specificity

Autor: Leroy Bondhus, Roshni Varma, Yenifer Hernandez, Valerie A Arboleda

Publikováno v: Briefings in bioinformatics, vol 23, iss 5

The spatial and temporal domain of a gene’s expression can range from ubiquitous to highly specific. Quantifying the degree to which this expression is unique to a specific tissue or developmental timepoint can provide insight into the etiology of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a234db73664928e475057559051c9ae
https://escholarship.org/uc/item/49p3f0b3

Statistical testing in transcriptomic-neuroimaging studies: A how-to and evaluation of methods assessing spatial and gene specificity

Autor: Dirk Jan Ardesch, Martijn P. van den Heuvel, Kyoko Watanabe, Siemon C. de Lange, Yongbin Wei, Rory Pijnenburg, Danielle Posthuma, Lianne H. Scholtens

Publikováno v: Human Brain Mapping, 43(3), 885-901. Wiley-Liss Inc.
Human Brain Mapping
Wei, Y, de Lange, S C, Pijnenburg, R, Scholtens, L H, Ardesch, D J, Watanabe, K, Posthuma, D & van den Heuvel, M P 2021, ' Statistical testing in transcriptomic-neuroimaging studies : A how-to and evaluation of methods assessing spatial and gene specificity ', Human Brain Mapping . https://doi.org/10.1002/hbm.25711
Human Brain Mapping, 43, 885-901. Wiley-Liss Inc.
Human Brain Mapping. Wiley-Liss Inc.
Wei, Y, de Lange, S C, Pijnenburg, R, Scholtens, L H, Ardesch, D J, Watanabe, K, Posthuma, D & van den Heuvel, M P 2022, ' Statistical testing in transcriptomic-neuroimaging studies : A how-to and evaluation of methods assessing spatial and gene specificity ', Human Brain Mapping, vol. 43, no. 3, pp. 885-901 . https://doi.org/10.1002/hbm.25711

Multiscale integration of gene transcriptomic and neuroimaging data is becoming a widely used approach for exploring the molecular underpinnings of large‐scale brain organization in health and disease. Proper statistical evaluation of determined as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bad23a2a898929d4180cff2812f0f9
https://research.vu.nl/en/publications/a7cd21cd-23f4-4fcd-9692-0ac4930c4c2f

Gap Junction Coding Innexin in Lymnaea stagnalis: Sequence Analysis and Characterization in Tissues and the Central Nervous System

Autor: Zhenguo Lin, Sonia N. Jolly, Fenglian Xu, Brittany A. Mersman

Publikováno v: Frontiers in Synaptic Neuroscience, Vol 12 (2020)

Connections between neurons called synapses are the key components underlying all nervous system functions of animals and humans. However, important genetic information on the formation and plasticity of one type, the electrical (gap junction-mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9046aba451df60cbf20338e988bbb6cb
https://www.frontiersin.org/article/10.3389/fnsyn.2020.00001/full

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