Zobrazeno 1 - 10
of 924
pro vyhledávání: '"gene inactivation"'
Autor:
R. A. Maksyutov, S. N. Yakubitskiy, I. V. Kolosova, T. V. Tregubchak, A. N. Shvalov, E. V. Gavrilova, S. N. Shchelkunov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 4, Pp 394-401 (2022)
Due to cessation of mass smallpox vaccination in 1980, the collective immunity of humans against orthopoxvirus infections has virtually been lost. Therefore, the risk of spreading zoonotic human orthopoxvirus infections caused by monkeypox and cowpox
Externí odkaz:
https://doaj.org/article/b529cf34cabf40fab9e8c17966d444e9
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CRISPR/Cas9 technology has revolutionized genetic engineering of primary cells. Although its use is gaining momentum in studies on CD8+ T cell biology, it remains elusive to what extent CRISPR/Cas9 affects in vivo function of CD8+ T cells. Here, we o
Externí odkaz:
https://doaj.org/article/53912e12b13440a18e9c110731cdbf79
Autor:
James B. Earl, Lauren A. Vanderlinden, Thomas L. Jacobsen, John C. Aldrich, Laura M. Saba, Steven G. Britt
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3949-3958 (2020)
Externí odkaz:
https://doaj.org/article/2afc080711a64ad3994b830043c9d8f6
Akademický článek
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Autor:
Younes Laidoudi, Edgarthe Priscilla Ngaiganam, Jean-Lou Marié, Isabelle Pagnier, Jean-Marc Rolain, Seydina Mouhamadou Diene, Bernard Davoust
Publikováno v:
Pathogens, Vol 11, Iss 9, p 1022 (2022)
Wild animals may act as efficient antimicrobial-resistance reservoirs and epidemiological links between humans, livestock, and natural environments. By using phenotypic and genotypic characterization, the present study highlighted the occurrence of a
Externí odkaz:
https://doaj.org/article/4dde1de4ebe34ef9bdd55214e9aca4a8
Autor:
Laurent Beuret, Simon-Pierre Fortier-Beaulieu, Vincent Rondeau, Sophie Roy, Nicolas Houde, Karl Balabanian, Marion Espéli, Jean Charron
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Several studies have established the crucial role of the extracellular signal–regulated kinase (ERK)/mitogen-activated protein kinase pathway in hematopoietic cell proliferation and differentiation. MEK1 and MEK2 phosphorylate and activate ERK1 and
Externí odkaz:
https://doaj.org/article/551a2b37afce409691d6b39eaab6cea2
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Nocamycins I and II, featured with a tetramic acid scaffold, were isolated from the broth of Saccharothrix syringae NRRL B-16468. The biosynthesis of nocamycin I require an intermediate bearing a hydroxyl group at the C-10 position. A short chain deh
Externí odkaz:
https://doaj.org/article/3be32c45f23b498093454697f0d9638c
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Base editing is a promising technique, allowing precise single-base mutagenesis in genomes without double-strand DNA breaks or donor templates. Cytosine base editors (CBEs) convert cytosine to thymidine. In particular, CBEs can transform fou
Externí odkaz:
https://doaj.org/article/5ca65d01d88c431994308779e20aff34
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Pseudomonas putida (P. putida) KT2440 is a paradigmatic environmental-bacterium that possesses significant potential in synthetic biology, metabolic engineering and biodegradation applications. However, most genome editing methods of P. putida KT2440
Externí odkaz:
https://doaj.org/article/0767dec162544e74967d21cf3fbc89a2
Autor:
Izumi, Tadahide, Brown, David B., Naidu, C. V., Bhakat, Kishor K., Macinnes, Mark A., Saito, Hiroshi, Chen, David J., Mitra, Sankar, Setlow, Richard B.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 Apr . 102(16), 5739-5743.
Externí odkaz:
https://www.jstor.org/stable/3375377