Recent advances in the characterization of essential genes and development of a database of essential genes

Autor: Ya‐Ting Liang, Hao Luo, Yan Lin, Feng Gao

Publikováno v: iMeta, Vol 3, Iss 1, Pp n/a-n/a (2024)

Abstract Over the past few decades, there has been a significant interest in the study of essential genes, which are crucial for the survival of an organism under specific environmental conditions and thus have practical applications in the fields of

Externí odkaz: https://doaj.org/article/51c62d967c78433282fecd6ca1081081

A Comprehensive Overview of Online Resources to Identify and Predict Bacterial Essential Genes

Autor: Chong Peng, Yan Lin, Hao Luo, Feng Gao

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

Genes critical for the survival or reproduction of an organism in certain circumstances are classified as essential genes. Essential genes play a significant role in deciphering the survival mechanism of life. They may be greatly applied to pharmaceu

Externí odkaz: https://doaj.org/article/dd7ef7a78bd749a8b795cc5fb68c69cd

Advances and perspectives in computational prediction of microbial gene essentiality

Autor: Mobegi, Fredrick M, Zomer, Aldert, de Jonge, Marien I, van Hijum, Sacha A F T, LS Klinisch Onderzoek Wagenaar, Sub Bioinformatics, Theoretical Biology and Bioinformatics, dI&I I&I-4

Publikováno v: Briefings in Functional Genomics, 16(2), 70. Oxford University Press
Briefings in Functional Genomics, 16, 70-79
Briefings in Functional Genomics, 16, 2, pp. 70-79

Item does not contain fulltext The minimal subset of genes required for cellular growth, survival and viability of an organism are classified as essential genes. Knowledge of essential genes gives insight into the core structure and functioning of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6778c34d8242be28e2bedc9d24b51e7a
https://doi.org/10.1093/bfgp/elv063

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Advances and perspectives in computational prediction of microbial gene essentiality.

Autor: Mobegi FM; Laboratory of Pediatric Infectious Diseases and Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Zomer A; Radboud university medical center, Laboratory of Pediatric Infectious Diseases, Nijmegen, The Netherlands.; Radboud university medical center, Bacterial Genomics Group; Center for Molecular and Biomolecular Informatics, Nijmegen, The Netherlands., de Jonge MI; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboudumc, Nijmegen, The Netherlands., van Hijum SA; Radboud Institute for Molecular Life Sciences, Laboratory of Paediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

Publikováno v: Briefings in functional genomics [Brief Funct Genomics] 2017 Mar 01; Vol. 16 (2), pp. 70-79.