Zobrazeno 1 - 10
of 117
pro vyhledávání: '"gene editing technology"'
Autor:
Qiang Feng, Qirong Li, Hengzong Zhou, Zhan Wang, Chao Lin, Ziping Jiang, Tianjia Liu, Dongxu Wang
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Gene editing is a growing gene engineering technique that allows accurate editing of a broad spectrum of gene‐regulated diseases to achieve curative treatment and also has the potential to be used as an adjunct to the conventional treatmen
Externí odkaz:
https://doaj.org/article/80a67480279941c19878dfb80f9e530d
Autor:
Essam Kerwash, John D. Johnston
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 906 (2024)
Casgevy (exa-cel) is an autologous cellular therapy modified ex vivo by a CRISPR-Cas9-mediated gene-editing technology. For Casgevy to be granted the indication in transfusion-dependent β-thalassemia, one single-arm trial was submitted which was not
Externí odkaz:
https://doaj.org/article/7abc92f213e64e9bbb69987a9b40a347
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Patient-derived autologous chimeric antigen receptor (CAR)-T cell therapy is a revolutionary breakthrough in immunotherapy and has made impressive progress in both preclinical and clinical studies. However, autologous CAR-T cells still have notable d
Externí odkaz:
https://doaj.org/article/3b821db9babb429b95c2839304624d3a
Publikováno v:
Foods, Vol 12, Iss 19, p 3681 (2023)
Effective regulation of gene-edited products and resolution of public concerns are the prerequisites for the industrialization of gene-edited crops and their derived foods. CRISPR-associated protein, the core element of the CRISPR system, requires to
Externí odkaz:
https://doaj.org/article/d65ecbdcaeb24808a0af79b82b881265
Autor:
Marit Svingen
Publikováno v:
Journal of Responsible Innovation, Vol 10, Iss 1 (2023)
ABSTRACTGene editing technologies like CRISPR have raised questions about the need for new regulations throughout Europe. In Norway, the Norwegian Biotechnology Advisory Board initiated a comprehensive process to formulate a proposal for a relaxation
Externí odkaz:
https://doaj.org/article/ce315e0ff64d472d84e744e6c1fd3711
Autor:
Huimin Zhang, Chunhong Qin, Changming An, Xiwang Zheng, Shuxin Wen, Wenjie Chen, Xianfang Liu, Zhenghua Lv, Pingchang Yang, Wei Xu, Wei Gao, Yongyan Wu
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-22 (2021)
Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna for the development of the Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease9 (CRISPR/Cas9) gene editing technolog
Externí odkaz:
https://doaj.org/article/75d998807ba64a88a19a032dba904f69
Publikováno v:
Di-san junyi daxue xuebao, Vol 43, Iss 18, Pp 1769-1774 (2021)
Objective To construct a GPR183 knockout mouse model by genome editing using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system, and to analyze the role of GPR183 receptor in lymphocyte regula
Externí odkaz:
https://doaj.org/article/840b24de4e934b0fac0f86a97ba603c6
Akademický článek
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Akademický článek
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Autor:
Xin-Zhu Chen, Rong Guo, Cong Zhao, Jing Xu, Hang Song, Hua Yu, Christian Pilarsky, Firzan Nainu, Jing-Quan Li, Xin-Ke Zhou, Jian-Ye Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer becomes one of the main causes of human deaths in the world due to the high incidence and mortality rate and produces serious economic burdens. With more and more attention is paid on cancer, its therapies are getting more of a concern. Previo
Externí odkaz:
https://doaj.org/article/766a520f64cb461aa91fed992631f3a1