Zobrazeno 1 - 10
of 170
pro vyhledávání: '"gene delivery vector"'
Autor:
Juan Yang, Guo-Feng Luo
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1696-1718 (2023)
Gene therapy is the ultimate therapeutic technology for diseases related to gene abnormality. However, the use of DNA alone has serious problems, such as poor stability and difficulty in entering target cells. The development of a safe and efficient
Externí odkaz:
https://doaj.org/article/983d43c6552c4836be7ee6428b2bdb33
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 2, Pp 128-138 (2023)
Cytokine-mediated cancer therapy has the potential to enhance immunotherapeutic approaches and cancer elimination plans through the endowing of the immune system by providing improved anticancer immunity. Despite the encouraging pioneer studies on in
Externí odkaz:
https://doaj.org/article/9a89d0786976458fa142bcdb1bec5735
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 491-501 (2022)
Adeno-associated viruses (AAVs) are useful vehicles for gene therapy because of their stability, low immunogenicity. and non-pathogenicity. However, disparity in AAV sample preparations (e.g., in capsid composition, DNA packaging, and impurities) giv
Externí odkaz:
https://doaj.org/article/0c58c4bafacb40d7a38d390c30024f28
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 40-47 (2022)
Adeno-associated viruses (AAVs) represent important gene therapy vectors with several approved clinical applications and numerous more in clinical trials. Genome packaging is an essential step in the bioprocessing of AAVs and needs to be tightly moni
Externí odkaz:
https://doaj.org/article/fa3c8d6616a241a5a4a1e0ede134507f
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Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Exploring safe and highly efficient gene carriers made from biocompatible constituents has great prospects for clinical gene therapy. Here, a supramolecular gene delivery system was readily constructed by assembling adamantyl-modified polyet
Externí odkaz:
https://doaj.org/article/f0d24ad00d8f446f99430f41261479a8
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 12, Iss 3, Pp 292-298 (2017)
A cationic gene delivery vector, guanidinylated disulfide-containing poly(amido amine) (CAR-CBA), was synthesized by Michael addition reaction between N,N′-cystaminebisacrylamide (CBA) and guanidine hydrochloride (CAR). Gel permeation chromatograph
Externí odkaz:
https://doaj.org/article/a7631f4ed7874b238e80ed21fa11ff7c
Autor:
Laura Nicolle, Jens Casper, Melanie Willimann, Céline M. A. Journot, Pascal Detampel, Tomaž Einfalt, Hiu Man Grisch-Chan, Beat Thöny, Sandrine Gerber-Lemaire, Jörg Huwyler
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3828 (2021)
There is an increasing interest in cationic polymers as important constituents of non-viral gene delivery vectors. In the present study, we developed a versatile synthetic route for the production of covalent polymeric conjugates consisting of water-
Externí odkaz:
https://doaj.org/article/833a41d6352e4dfb8f3a861ccffc8da6
Publikováno v:
International Journal of Nanomedicine, Vol 2016, Iss default, Pp 1013-1023 (2016)
Yanni Yu,1 Yongpei Hu,1 Xiufang Li,1 Yu Liu,1 Mingzhong Li,1 Jicheng Yang,2 Weihua Sheng2 1National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, 2Cell and Molecular Biology Institute, Colleg
Externí odkaz:
https://doaj.org/article/60e8acc4343e44d0ace3fa52dd99248c
Autor:
Andrea Elizabeth Verna, Valentina Franceschi, Giulia Tebaldi, Francesca Macchi, Valentina Menozzi, Claudia Pastori, Lucia Lopalco, Simone Ottonello, Sandro Cavirani, Gaetano Donofrio
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Bovine herpesvirus 4 (BoHV-4) is a promising vector for the delivery and intracellular expression of recombinant antigens and can thus be considered as a new prototype vaccine formulation system. An interesting, and actively pursued, antigen in the c
Externí odkaz:
https://doaj.org/article/b4070a21624548d288ecd11298d433c3