Zobrazeno 1 - 10
of 561
pro vyhledávání: '"gene circuits"'
Autor:
Angus Armstrong, Mark Isalan
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Over the past 2 decades, rapid advances in synthetic biology have enabled the design of increasingly intricate and biologically relevant systems with broad applications in healthcare. A growing area of interest is in designing bacteria that sense and
Externí odkaz:
https://doaj.org/article/820f0f4f4921403f95d13fa725ade875
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35050- (2024)
Sensors used in precision agriculture for the detection of heavy metals in irrigation water are generally expensive and sometimes their deployment and maintenance represent a permanent investment to keep them in operation, leaving a lasting polluting
Externí odkaz:
https://doaj.org/article/eaa1fac549194f888827f17b340e21e8
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Despite the array of mammalian transgene switches available for regulating therapeutic protein expression in response to small molecules or physical stimuli, issues remain, including cytotoxicity of chemical inducers and limited biocompatibi
Externí odkaz:
https://doaj.org/article/81ea40474b714dc988a9eff638868201
Autor:
Roee Samuel, Ramez Daniel
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
In recent years, the use of gene therapy for the treatment of disease has gained substantial interest, both in academic research and in the biomedical industry. Initial experimentation in gene therapy has generated positive results, as well as questi
Externí odkaz:
https://doaj.org/article/773e47af63144bd58d952d578df00c1b
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 946-949 (2023)
Synthetic biology has made it possible to rewire natural cellular responses to treat disease, notably demonstrated by chimeric antigen receptor (CAR) T cells as cancer immunotherapy. Building on the success of T‐cell activation using synthetic rece
Externí odkaz:
https://doaj.org/article/ccc31952cdbc4b9bb5494cb6648da9f3
Autor:
Zhuo Feng, Yuchen Wang, Haiheng Xu, Yunfei Guo, Wen Xia, Chenxuan Zhao, Xiaozhi Zhao, Jinhui Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1014-1027 (2023)
Intelligent drug delivery is a promising strategy for cancer therapies. In recent years, with the rapid development of synthetic biology, some properties of bacteria, such as gene operability, excellent tumor colonization ability, and host-independen
Externí odkaz:
https://doaj.org/article/29154f16f9b84e38a93a2f3f73479c6e
Autor:
Laura Prochazka, Yale S Michaels, Charles Lau, Ross D Jones, Mona Siu, Ting Yin, Diana Wu, Esther Jang, Mercedes Vázquez‐Cantú, Penney M Gilbert, Himanshu Kaul, Yaakov Benenson, Peter W Zandstra
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 11, Pp 1-22 (2022)
Abstract During development, cell state transitions are coordinated through changes in the identity of molecular regulators in a cell type‐ and dose‐specific manner. The ability to rationally engineer such transitions in human pluripotent stem ce
Externí odkaz:
https://doaj.org/article/e2b62297353c4d7b84600c9edd7e25df
Akademický článek
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Akademický článek
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Publikováno v:
Fermentation, Vol 9, Iss 4, p 341 (2023)
Biocontainment techniques for genetically modified yeasts (GMYs) are pivotal due to the importance of these organisms for biotechnological processes and also due to the design of new yeast strains by using synthetic biology tools and technologies. Du
Externí odkaz:
https://doaj.org/article/873c87a126b34928aa988f660b5e0d67