Zobrazeno 1 - 10
of 2 736
pro vyhledávání: '"gene analysis"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Dysbiosis of the gut-liver axis increases the risk of bacterial and metabolite influx into the liver, which may contribute to the development of hepatocellular carcinoma (HCC). In this study, we compared the microbiomes in HCC tumors and adj
Externí odkaz:
https://doaj.org/article/62964c7eb07741b198e0e521513e275e
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract This study investigates NADPH oxidase 4 (NOX4) involvement in iron-mediated astrocyte cell death in Alzheimer’s Disease (AD) using single-cell sequencing data and transcriptomes. We analyzed AD single-cell RNA sequencing data, identified a
Externí odkaz:
https://doaj.org/article/d935a1a61eb54ab9b0bf54f56fe1169c
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Current RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering species-specific differences. However, the suitability and accuracy of these tools may vary when analy
Externí odkaz:
https://doaj.org/article/3a51cfa367b9433ca3a5be7539e3f80a
Autor:
Li Long, Jue Li, Linyu Huang, Huiling Jin, Fangnian Guan, Haipeng Zhang, Sasa Zhao, Hao Li, Zhien Pu, Wei Li, Qiantao Jiang, Yuming Wei, Jian Ma, Houyang Kang, Shoufen Dai, Pengfei Qi, Qiang Xu, Mei Deng, Youliang Zheng, Yunfeng Jiang, Matthew James Moscou, Guoyue Chen
Publikováno v:
Crop Journal, Vol 12, Iss 3, Pp 826-835 (2024)
Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a devastating disease in wheat worldwide. Discovering and characterizing new resistance genes/QTL is crucial for wheat breeding programs. In this study, we fine-mapped and character
Externí odkaz:
https://doaj.org/article/485be0d7c6a045128ddb236772192755
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
For many industrial chemicals toxicological data is sparse regarding several regulatory endpoints, so there is a high and often unmet demand for NAMs that allow for screening and prioritization of these chemicals. In this proof of concept case study
Externí odkaz:
https://doaj.org/article/7824a62fc0ef41bfba6176412284a191
Autor:
Jingmeng Liu, Taojie Zhou, Yangyang Bao, Changjian Lin, Qiujing Chen, Yang Dai, Ning Zhang, Wenqi Pan, Qi Jin, Lin Lu, Qiang Zhao, Tianyou Ling, Liqun Wu
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e37366- (2024)
Background: Cellular senescence is pivotal in the occurrence and progression of atrial fibrillation (AF). This study aimed to identify senescence-related genes that could be potential therapeutic biomarkers for AF. Methods: AF-related differentially
Externí odkaz:
https://doaj.org/article/5aa45abed98c43d1836b588dd9a19e3d
Autor:
Elsayed I. Salim, Mona M. Alabasy, Eman M. El Nashar, Norah S. Al-Zahrani, Mohammed A. Alzahrani, Zihu Guo, Doha M. Beltagy, Mohamed Shahen
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Cancer is a fatal disease that severely affects humans. Designing new anticancer strategies and understanding the mechanism of action of anticancer agents is imperative. Hypothesis/Purpose In this study, we evaluated the utility o
Externí odkaz:
https://doaj.org/article/266bd624421c42bdbdf3708ab01cba88
Autor:
Romualdus Nugraha Catur Utomo, Alena Lisa Palkowitz, Lin Gan, Anna Rudzinski, Julia Franzen, Hendrik Ballerstedt, Martin Zimmermann, Lars Mathias Blank, Horst Fischer, Stefan Wolfart, Taskin Tuna
Publikováno v:
Journal of Oral Microbiology, Vol 16, Iss 1 (2024)
Background Biofilm formation on implant-abutment surfaces can cause inflammatory reactions. Ethical concerns often limit intraoral testing, necessitating preliminary in vitro or animal studies. Here, we propose an in vitro model using human saliva an
Externí odkaz:
https://doaj.org/article/cb9979240f5c484e904cbcf6b764468a
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33648- (2024)
The pathogenesis of rheumatoid arthritis (RA) remains elusive. The initiation of joint degeneration is characterized by the loss of self-tolerance in peripheral joints. Ferroptosis, a form of regulated cell death, holds significant importance in the
Externí odkaz:
https://doaj.org/article/889e63aa6a3f42edbca5a8a2ef6bfb4e