Zobrazeno 1 - 10
of 10 229
pro vyhledávání: '"gbm"'
Autor:
Muhammad Naveed, Sarmad Mahmood, Tariq Aziz, Arooj Azeem, Zeerwah Rajpoot, Shafiq ur Rehman, Fahad Al-Asmari, Amirah S. Alahmari, Ohud Saleh, Manal Y. Sameeh, Majid Alhomrani, Abdulhakeem S. Alamri, Sahar A. Alshareef
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Brain tumors, particularly Glioblastoma Multiforme (GBM) and Low-Grade Gliomas (LGG), present significant clinical challenges due to their aggressive nature and resistance to conventional treatments. Traditional therapies such as surgery, ch
Externí odkaz:
https://doaj.org/article/ddd25fbba94d4715af1ffe41aac5430a
Autor:
Jingwen Xiong, Xuancheng Zhou, Lanqian Su, Lai Jiang, Ziwei Ming, Can Pang, Claire Fuller, Ke Xu, Hao Chi, Xiaomei Zheng
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Gliomas are the most common primary malignant tumours of the central nervous system (CNS), which are highly aggressive, with increasing morbidity and mortality rates year after year, posing a serious threat to the quality and expected surviv
Externí odkaz:
https://doaj.org/article/1c61fbfd43ba4fef8fb3ba9dcdc325b8
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 381-97 (2024)
The poor surgical efficacy and recurrence of glioblastoma (GBM) are due to its lack of visible infiltrative features. Our bioinformatics study suggests that low expression of small ubiquitin-like modifier (SUMO)-specific protease 7 (SENP7) indicates
Externí odkaz:
https://doaj.org/article/e81b98529177452981cf93ad839896c0
Autor:
S. John Liu, Christopher Zou, Joanna Pak, Alexandra Morse, Dillon Pang, Timothy Casey-Clyde, Ashir A. Borah, David Wu, Kyounghee Seo, Thomas O’Loughlin, Daniel A. Lim, Tomoko Ozawa, Mitchel S. Berger, Roarke A. Kamber, William A. Weiss, David R. Raleigh, Luke A. Gilbert
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-32 (2024)
Abstract Background Genetic perturbation screens with single-cell readouts have enabled rich phenotyping of gene function and regulatory networks. These approaches have been challenging in vivo, especially in adult disease models such as cancer, whic
Externí odkaz:
https://doaj.org/article/ce15256d82df4ae7a07d376548cbf5c6
Autor:
Yang Xing, Feroza Yasinjan, Huayue Geng, Minghua He, Mei Yang, Yufei Gao, Jinnan Zhang, Ling Zhang, Baofeng Guo
Publikováno v:
Asian Journal of Surgery, Vol 47, Iss 10, Pp 4271-4280 (2024)
Gliomas are the most prevalent primary malignant brain tumors worldwide, with glioblastoma (GBM) being the most common and aggressive type. The standard therapy for GBM has remained unchanged for nearly two decades, with no significant improvement in
Externí odkaz:
https://doaj.org/article/3f6aaaa4a6cf4ad389b6b6d09aa80d34
Publikováno v:
Geomechanics and Geophysics for Geo-Energy and Geo-Resources, Vol 10, Iss 1, Pp 1-21 (2024)
Abstract Studying crystal anisotropy is of great importance for understanding the thermal–mechanical coupling behavior of crystalline rocks in deep underground engineering. In this study, a microscopic parameter calibration method incorporating the
Externí odkaz:
https://doaj.org/article/c7eb140d3d7e4cfa9448399b74ba8a53
Autor:
Caohang Qiu, Ning Sun, Shan Zeng, Ligang Chen, Feilong Gong, Junjie Tian, Yu Xiong, Lilei Peng, Haiping He, Yang Ming
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Glioblastoma (GBM), a primary brain tumor, exhibits remarkable invasiveness and is characterized by its intricate location, infiltrative behavior, the presence of both the blood–brain barrier (BBB) and the blood–brain tumor barrier (BBTB
Externí odkaz:
https://doaj.org/article/e320d28057f74b0a8ce7536a0c3959e5
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Glioblastoma multiforme (GBM) is a highly aggressive primary malignant brain tumor characterized by rapid progression, poor prognosis, and high mortality rates. Understanding the relationship between cerebrospinal fluid (CSF) meta
Externí odkaz:
https://doaj.org/article/be4fc2b4f593410f8f28ad764db79616
Autor:
Francesca Giammello, Chiara Biella, Erica Cecilia Priori, Matilde Amat Di San Filippo, Roberta Leone, Francesca D’Ambrosio, Martina Paterno’, Giulia Cassioli, Antea Minetti, Francesca Macchi, Cristina Spalletti, Ilaria Morella, Cristina Ruberti, Beatrice Tremonti, Federica Barbieri, Giuseppe Lombardi, Riccardo Brambilla, Tullio Florio, Rossella Galli, Paola Rossi, Federico Brandalise
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract Background Glioblastoma (GBM) stands as the most prevalent and aggressive form of adult gliomas. Despite the implementation of intensive therapeutic approaches involving surgery, radiation, and chemotherapy, Glioblastoma Stem Cells contribut
Externí odkaz:
https://doaj.org/article/f620b5142f8b4c7d9c81860a86cd23a7
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Glioblastoma (GBM) is a malignant astrocytic tumor and its progression involves the regulation of vascular endothelial growth factor-A (VEGFA). However, the mechanism of VEGFA in regulating GBM progression remains unclear. Methods
Externí odkaz:
https://doaj.org/article/f92603400b7e48cb8541712ef534d2d7