Zobrazeno 1 - 10
of 1 285
pro vyhledávání: '"gated potassium channels"'
Autor:
Ana Martinez, Sophie Binks, Martí Pumarola, Alexandros Hardas, Alistair Easton, Leticia Campo, Molly Browne, Susana Martins, Laurent S. Garosi, Francesco Di Dona, Anna Tauro
Publikováno v:
Clinical Case Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Key Clinical Message Gliosarcoma, a rare cerebral neoplasm, has not been linked to hippocampal changes in cats. We report a case of complex partial seizures with orofacial involvement, revealing gliosarcoma concurrent with bilateral hippocampal scler
Externí odkaz:
https://doaj.org/article/20f7457ec2b042e3956921d082ca554d
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Traumatic spinal cord injury (SCI) results in immediate tissue necrosis and delayed secondary expansion of neurological damage, often resulting in lifelong paralysis, neurosensory dysfunction, and chronic pain. Progressive hemorrhagic necrosis (PHN)
Externí odkaz:
https://doaj.org/article/43a21c2018444e2da7f0778f44e1162c
Autor:
Gerald Z. Zhuang, William F. Goins, Munal B. Kandel, Marco Marzulli, Mingdi Zhang, Joseph C. Glorioso, Yuan Kang, Alexandra E. Levitt, Konstantinos D. Sarantopoulos, Roy C. Levitt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Chronic pain is common in our population, and most of these patients are inadequately treated, making the development of safer analgesics a high priority. Knee osteoarthritis (OA) is a primary cause of chronic pain and disability worldwide, and lower
Externí odkaz:
https://doaj.org/article/3c57fab413674ae6984ae5fb58a321ff
Autor:
Seok Kyu Kang, Nicole A. Hawkins, Christopher H. Thompson, Erin M. Baker, Dennis M. Echevarria-Cooper, Levi Barse, Tyler Thenstedt, Conor J. Dixon, Nathan Speakes, Alfred L. George, Jr, Jennifer A. Kearney
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106470- (2024)
Pathogenic variants in KCNB1 are associated with a neurodevelopmental disorder spectrum that includes global developmental delays, cognitive impairment, abnormal electroencephalogram (EEG) patterns, and epilepsy with variable age of onset and severit
Externí odkaz:
https://doaj.org/article/4b98448bbf9f4c469dfa4fe4876231d8
Autor:
Munal B. Kandel, Gerald Z. Zhuang, William F. Goins, Marco Marzulli, Mingdi Zhang, Joseph C. Glorioso, Yuan Kang, Alexandra E. Levitt, Wai-Meng Kwok, Roy C. Levitt, Konstantinos D. Sarantopoulos
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Chronic pain is common and inadequately treated, making the development of safe and effective analgesics a high priority. Our previous data indicate that carbonic anhydrase-8 (CA8) expression in dorsal root ganglia (DRG) mediates analgesia via inhibi
Externí odkaz:
https://doaj.org/article/3621c8f032f6429ba118a169c8a8463e
Autor:
Rita Turcio, Francesca Di Matteo, Ilaria Capolupo, Tania Ciaglia, Simona Musella, Carla Di Chio, Claudio Stagno, Pietro Campiglia, Alessia Bertamino, Carmine Ostacolo
Publikováno v:
Marine Drugs, Vol 22, Iss 8, p 350 (2024)
Bioactive compounds are abundant in animals originating from marine ecosystems. Ion channels, which include sodium, potassium, calcium, and chloride, together with their numerous variants and subtypes, are the primary molecular targets of the latter.
Externí odkaz:
https://doaj.org/article/5a0257501d444c2c9cd23465758cfb2f
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 37, Iss 1 (2023)
AbstractSertoli cells constitutively maintain the spermatogonial stem cell niche and blood-testis barrier via impenetrable tight junctions under hormonal, growth factor and cytokine control. Immature Sertoli cell proliferation and survival benefit fr
Externí odkaz:
https://doaj.org/article/0948a88ee6f648218cd62c58340a060f
Autor:
Jonathan D. Enders, Sarah Thomas, Paige Lynch, Jarrid Jack, Janelle M. Ryals, Patrycja Puchalska, Peter Crawford, Douglas E. Wright
Publikováno v:
Neurobiology of Pain, Vol 14, Iss , Pp 100138- (2023)
Chronic pain is a substantial health burden and options for treating chronic pain remain minimally effective. Ketogenic diets are emerging as well-tolerated, effective therapeutic strategies in preclinical models of chronic pain, especially diabetic
Externí odkaz:
https://doaj.org/article/9d3789feed774fa9ba4c75502423dace
Publikováno v:
Toxins, Vol 16, Iss 3, p 118 (2024)
Ciguatoxins (CTXs) are neurotoxins responsible for ciguatera poisoning (CP), which affects more than 50,000 people worldwide annually. The development of analytical methods to prevent CP is a pressing global issue, and the N2a assay is one of the mos
Externí odkaz:
https://doaj.org/article/70e401157ed24330bac2c4777e1d8e7d
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