Zobrazeno 1 - 10
of 663
pro vyhledávání: '"gamma-tocotrienol"'
Autor:
Neetha Nanoth Vellichirammal, Sahil Sethi, Nagavardhini Avuthu, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda, Vijay K. Singh
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract The risk of exposure of the general public or military personnel to high levels of ionizing radiation from nuclear weapons or radiological accidents is a dire national security matter. The development of advanced molecular biodosimetry metho
Externí odkaz:
https://doaj.org/article/99c4a7b85d414c0bbcf85c39bfb8bbfe
Autor:
Stephen A. Shrum, Ujwani Nukala, Shivangi Shrimali, Edith Nathalie Pineda, Kimberly J. Krager, Shraddha Thakkar, Darin E. Jones, Rupak Pathak, Philip J. Breen, Nukhet Aykin-Burns, Cesar M. Compadre
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1987 (2023)
Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation countermeasures. To facilitate their development as clinical radiation countermeasures, it
Externí odkaz:
https://doaj.org/article/025774aeb31a47a8886e67dfde8f0adf
Akademický článek
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Autor:
Muhammad Naveed, Noor ul Ain, Tariq Aziz, Khushbakht Javed, Muhammad Aqib Shabbir, Metab Alharbi, Abdulrahman Alsahammari, Abdullah F. Alasmari
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1041 (2023)
BCR-ABL1 is a fusion protein as a result of a unique chromosomal translocation (producing the so-called Philadelphia chromosome) that serves as a clinical biomarker primarily for chronic myeloid leukemia (CML); the Philadelphia chromosome also occurs
Externí odkaz:
https://doaj.org/article/cdaefa3d1eac4c0988acea52a9302446
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 169-174 (2021)
DNA methylation plays a crucial role in polarising naïve lymphocytes towards their various sub-populations to fight against many immune challenges including establishment of tumour. Gamma-tocotrienol (γT3) is a natural form of vitamin E, reported t
Externí odkaz:
https://doaj.org/article/efc225b4216f42a19223fe4c5b24cb39
Autor:
Tarun K. Garg, Sarita Garg, Isabelle R. Miousse, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Frits van Rhee, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16170 (2022)
Radiation exposure causes acute damage to hematopoietic and immune cells. To date, there are no radioprotectors available to mitigate hematopoietic injury after radiation exposure. Gamma-tocotrienol (GT3) has demonstrated promising radioprotective ef
Externí odkaz:
https://doaj.org/article/ef7776838a0b4613be3f43b6c959d0c1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b5e5eb9cf902431ba4c2853962f1688b
Autor:
Sarita Garg, Tarun K. Garg, Isabelle R. Miousse, Stephen Y. Wise, Oluseyi O. Fatanmi, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1895 (2022)
Exposure to high doses of radiation, accidental or therapeutic, often results in gastrointestinal (GI) injury. To date, there are no therapies available to mitigate GI injury after radiation exposure. Gamma-tocotrienol (GT3) is a promising radioprote
Externí odkaz:
https://doaj.org/article/0172642cac77426eb4f9fb4893f02c6a
Autor:
Kyoung-Woon Kim, Bo-Mi Kim, Ji-Yeon Won, Hong Ki Min, Seoung Joon Lee, Sang-Heon Lee, Hae-Rim Kim
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss Suppl 1, Pp S273-S282 (2021)
Background/Aims The present study aimed to investigate whether tocotrienol regulates interleukin 17 (IL-17)-induced osteoclastogenesis in rheumatoid arthritis (RA). Methods We evaluated the effect of tocotrienol on IL-17-induced receptor activator of
Externí odkaz:
https://doaj.org/article/e256048e131747d58b3a8ea7be05a418
Autor:
Sarita Garg, Tarun K. Garg, Stephen Y. Wise, Oluseyi O. Fatanmi, Isabelle R. Miousse, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4643 (2022)
The gastrointestinal (GI) system is highly susceptible to irradiation. Currently, there is no Food and Drug Administration (FDA)-approved medical countermeasures for GI radiation injury. The vitamin E analog gamma-tocotrienol (GT3) is a promising rad
Externí odkaz:
https://doaj.org/article/04d67ca2d012410cb023228e34be9a37