Direct effect of 2‐palmitoyl glycerol on promotion of gamma aminobutyric acid synthesis in normal human fetal‐derived astrocytes

Autor: Misato Tsuboi, Yoshitaka Nakamura, Hiroshi Sakuma

Publikováno v: FEBS Open Bio, Vol 13, Iss 7, Pp 1320-1332 (2023)

Breast milk contains constituents, such as 1,3‐dioleoyl‐2‐palmitoylglycerol (OPO), that are beneficial for infants. Herein, we hypothesized that 2‐palmitoyl glycerol (2‐PG), a derivative of OPO, is advantageous to infants' development. Gamm

Externí odkaz: https://doaj.org/article/e6c4e202525f4a6283891b054c7597cb

Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus

Autor: Abdel-Rahman Al-Absi, Sakeerthi Kethees Thambiappa, Ahmad Raza Khan, Simon Glerup, Connie Sanchez, Anne M. Landau, Jens R. Nyengaard

Publikováno v: Al-Absi, A-R, Thambiappa, S K, Khan, A R, Glerup, S, Sanchez, C, Landau, A M & Nyengaard, J R 2022, ' Df(h22q11)/+ mouse model exhibits reduced binding levels of GABA A receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus ', Molecular and Cellular Neuroscience, vol. 122, 103769 . https://doi.org/10.1016/j.mcn.2022.103769

The 22q11.2 hemizygous deletion confers high risk for multiple neurodevelopmental disorders. Inhibitory signaling, largely regulated through GABAA receptors, is suggested to serve a multitude of brain functions that are disrupted in the 22q11.2 delet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4344b1f2a65a4089b17af752d2f9afc1
https://pure.au.dk/portal/da/publications/dfh22q11-mouse-model-exhibits-reduced-binding-levels-of-gabaa-receptors-and-structural-and-functional-dysregulation-in-the-inhibitory-and-excitatory-networks-of-hippocampus(df609e60-3951-4037-8a8f-bdaa111813d5).html

Sleep disturbance in PTSD and other anxiety-related disorders: an updated review of clinical features, physiological characteristics, and psychological and neurobiological mechanisms

Autor: Thomas C. Neylan, Jennifer C. Kanady, Anne Richards

Publikováno v: Neuropsychopharmacology

The current report provides an updated review of sleep disturbance in posttraumatic stress disorder and anxiety-related disorders. First, this review provides a summary description of the unique and overlapping clinical characteristics and physiologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d47224e947556bda366b13dcd8ffc6e
https://doi.org/10.1038/s41386-019-0486-5

LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons

Autor: Fang Yuan, Shi-Bo Xu, Kai-Heng Fang, Yufeng Pan, Min Xu, Yuan Hong, Yan Liu

Publikováno v: Protein & Cell
Protein & Cell, Vol 11, Iss 4, Pp 286-291 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084c84f8517a567d65a401c92db81d96
https://pubmed.ncbi.nlm.nih.gov/31907793

Cuprizone-treated mice, a possible model of schizophrenia, highlighting the simultaneous abnormalities of GABA, serine and glycine in hippocampus

Autor: Takahiro A. Kato, Shigenobu Kanba, Masahiro Ohgidani, Daisuke Miura, Eisuke Hayakawa, Yoshinori Fujimura

Publikováno v: Schizophrenia Research. 210:326-328

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b139696c980db20b10cb841fe66a5970
https://doi.org/10.1016/j.schres.2019.06.010