Zobrazeno 1 - 10
of 3 546
pro vyhledávání: '"galectin-1"'
Autor:
Nikolay E. Kushlinskii, Olga V. Kovaleva, Arseniy G. Basov, Yurii B. Kuzmin, Aleksandr A. Alferov, Svetlana D. Bezhanova, Aleksey V. Kolpashchikov, Igor A. Klimanov, Alexey N. Grachev, Natalia N. Zybina, Vsevolod B. Matveev, Oleg O. Yanushevich, Ivan S. Stilidi
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 107-119 (2024)
Background: Galectins are a family of β-galactoside binding proteins that regulate the vast majority of cellular functions, including proliferation, migration, adhesion, and phagocytosis in both health and disease. More and more experimental and cli
Externí odkaz:
https://doaj.org/article/3dc7de3dbc9b49969eb33690ddc7e80c
Autor:
Olga I. Urazova, Gleb V. Reyngardt, Yulia V. Kolobovnikova, Anna V. Kurnosenko, Vadim S. Poletika, Olga A. Vasil'yeva, Aleksandra V. Avgustinovich
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 170-177 (2024)
Background: Galectin-1 plays an important role in the pathogenesis of colorectal cancer (CRC). The blood and tumoral levels of galectin-1 could be dependent on the polymorphism of the promotor region of LGALS1 gene. Aim: To analyze an association
Externí odkaz:
https://doaj.org/article/831cb4f5d01f40718a489e6114cadafe
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 207-225 (2024)
Modulating inflammatory cells in an implantation site leads to severe complications and still unsolved challenges for blood-contacting medical devices. Inspired by the role of galectin-1 (Gal-1) in selective functions on multiple cells and immunomodu
Externí odkaz:
https://doaj.org/article/f669699eb57940c6a52fa114128922a3
Autor:
Ahmad Shaikh, Arunakumar Gangaplara, Abdoul Kone, Katherine Almengo, Mariama D. Kabore, Mohamed A.E. Ali, Xin Xu, Ankit Saxena, Maria Lopez-Ocasio, J. Philip McCoy, Courtney D. Fitzhugh
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Haploidentical hematopoietic cell transplantation (haplo-HCT) is associated with an increased risk of allograft rejection. Here, we employed a major histocompatibility complex (MHC)-mismatched allogeneic HCT (allo-HCT) murine model to better understa
Externí odkaz:
https://doaj.org/article/24e35174d94942e4b4ebfeee39393ccf
Akademický článek
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Autor:
Sridhar Goud Nerella
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 11, Iss , Pp 100170- (2024)
Galectin-1 (gal-1) emerges as a potential biomarker for cancer diagnosis, prognosis, and therapy. Gal-1 plays a pivotal role in multiple stages of tumor progression, encompassing tumor transformation, tumor cell adhesion and migration, angiogenesis,
Externí odkaz:
https://doaj.org/article/aeba2c4fd2b24b508df7aeeacc205831
Autor:
Hsiao-Chi Wang, Roger Xia, Wen-Hsin Chang, Ssu-Wei Hsu, Chun-Te Wu, Ching-Hsien Chen, Tsung-Chieh Shih
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Our study aimed to elucidate the role of Galectin-1 (Gal-1) role in the immunosuppressive tumor microenvironment (TME) of prostate cancer (PCa). Our previous findings demonstrated a correlation between elevated Gal-1 expression and advanced PCa stage
Externí odkaz:
https://doaj.org/article/55900c570dd846cc8459fe7980bdaeab
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 2, Pp 100455- (2024)
Objective: We tested the potential of circulating galectin-1, interleukin (IL)-1 beta, IL-6, and tumour necrosis factor alpha (TNF alpha) levels at baseline in individuals with knee pain as biomarkers for development of radiographic knee and/or hand
Externí odkaz:
https://doaj.org/article/36f107be35b940ddbaefb6500ec61d38
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Chimeric antigen receptor (CAR) T cells have shown significant activity in B-lineage malignancies. However, their efficacy in myeloid leukemia has not been successful due to unclear molecular mechanisms. Methods We conducted in vi
Externí odkaz:
https://doaj.org/article/c95949042a0c4c92a916746253a9f011
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Background In renal cell carcinoma (RCC), no clinically available biomarker has been utilized for checkpoint inhibitor immunotherapy (IO) + tyrosine kinase inhibitor (TKI) combinations. Galectin‐1 overexpression is found in tumors, with po
Externí odkaz:
https://doaj.org/article/34b92b445129434aaa8bcf0930df2070