Differential effect on myelination through abolition of activity‐dependent synaptic vesicle release or reduction of overall electrical activity of selected cortical projections in the mouse

Autor: Korrell, KV, Disser, J, Parley, K, Vadisiute, A, Requena-Komura, M-C, Fodder, H, Pollart, C, Knott, G, Molnar, Z, Hoerder-Suabedissen, A

Publikováno v: Journal of Anatomy
Journal of anatomy, 235 (3

Myelination of axons by oligodendrocytes in the central nervous system is crucial for fast, saltatory conduction of action potentials. As myelination is central for brain development and plasticity, and deficits are implicated in several neural disor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5ce6d5799670c70f7c3cc7a5302093d6
http://europepmc.org/articles/PMC6704270

Etude du rôle des facteurs de transcription Dmrt3 et Dmrt5 dans le développement cortical: Dmrt3 et Dmrt5 maintiennent l'identité corticale dans les progéniteurs du télencéphale dorsal au cours du développement

Autor: Desmaris, Elodie

La spécification de l’identité ventrale ou dorsale des progéniteurs au cours du développement du télencéphale est la première étape cruciale du développement du cortex cérébral. Les gènes doublesex and mab-3 related (Dmrt) Dmrt3 et Dmrt

Externí odkaz: https://dipot.ulb.ac.be/dspace/bitstream/2013/309310/5/ContratDiDesmaris.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/309310/3/EFDesmaristabledesmatieres.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/309310/4/EFDesmaristhesis.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/309310

Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

Autor: Marco Bugliani, François Fuks, Miriam Cnop, Silva A. Arslanian, Jamie L. Felton, Raghavendra G. Mirmira, Farooq Syed, Kieren J. Mather, Ezio Bonifacio, Nicole Jiyun Kang, Anette-Gabriele Ziegler, Mathieu Defrance, Sarah A. Tersey, Carmella Evans-Molina, Appakalai N. Balamurugan, Jennifer Nelson, Jean-Valery Turatsinze, Decio L. Eizirik, Emily K. Sims, Bobbie-Jo M. Webb-Robertson, Martin Bizet, Piero Marchetti

Publikováno v: Clinical Epigenetics
Clinical Epigenetics, 12 (1

BACKGROUND: Identification of islet β cell death prior to the onset of type 1 diabetes (T1D) or type 2 diabetes (T2D) might allow for interventions to protect β cells and reduce diabetes risk. Circulating unmethylated DNA fragments arising from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c676f69347d95c5a5c1ee715c3f708
https://pubmed.ncbi.nlm.nih.gov/32736653

SUMOylation, a multifaceted regulatory mechanism in the pancreatic beta cells

Autor: Decio L. Eizirik, Na Li, Cong-Yi Wang, Fei Xiong, Shu Zhang

Publikováno v: Seminars in cell & developmental biology

SUMOylation is an evolutionarily conserved post-translational modification (PTM) that regulates protein subcellular localization, stability, conformation, transcription and enzymatic activity. Recent studies indicate that SUMOylation plays a key role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2252b927f80521b284bf50e426fdbe1
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/307282

Cardiopharyngeal progenitor specification: multiple roads to the heart and head muscles

Autor: Fabienne Lescroart, Benjamin Swedlund

Publikováno v: Heart Development and Disease
Heart Development and Disease, 2019, 978-1-621823-58-2
Cold Spring Harb Perspect Biol
Cold Spring Harbor Perspectives in Biology

International audience; During embryonic development, the heartarise from various sourcesof undifferentiated mesodermal progenitors, with an additional contribution from ectodermal neural crest cells. Mesodermal cardiac progenitorsareplasticand multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eaede10ccce221a05cdddc7d6c78a5c
https://hal-amu.archives-ouvertes.fr/hal-02440680