Zobrazeno 1 - 10
of 485
pro vyhledávání: '"fzd4"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundProstate cancer (PCa) ranks as the second leading cause of cancer-related mortality among men. Long non-coding RNAs (lncRNAs) are known to play a regulatory role in the development of various human cancers. LncRNA MAFG-divergent transcript
Externí odkaz:
https://doaj.org/article/9c70b17d00204deab353c706cdac30a4
Autor:
Fenghua Bian, Chinmayee Goda, Guolun Wang, Ying-Wei Lan, Zicheng Deng, Wen Gao, Anusha Acharya, Abid A Reza, Jose Gomez-Arroyo, Nawal Merjaneh, Xiaomeng Ren, Jermaine Goveia, Peter Carmeliet, Vladimir V Kalinichenko, Tanya V Kalin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 5, Pp 1063-1090 (2024)
Abstract Cancer cells re-program normal lung endothelial cells (EC) into tumor-associated endothelial cells (TEC) that form leaky vessels supporting carcinogenesis. Transcriptional regulators that control the reprogramming of EC into TEC are poorly u
Externí odkaz:
https://doaj.org/article/5439a6cbb06e4ec08ebc2c470e7a8041
Autor:
Jianbo Mao, Yijing Chen, Yuyan Fang, Yirun Shao, Ziyi Xiang, Hanxiao Li, Shixin Zhao, Yiqi Chen, Lijun Shen
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 3286-3298 (2022)
Objective To explore the clinical manifestations and search for the variants of six related genes (LRP5, FZD4, TSPAN12, NDP, KIF11 and ZNF408) in Chinese patients with familial exudative vitreoretinopathy (FEVR), and investigate the correlation betwe
Externí odkaz:
https://doaj.org/article/b8ab89b14f6c447da1f206c83f925ea3
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Introduction Accumulating evidence highlights the critical roles of circular RNAs (circRNAs) in the malignant progression of cancers. In this study, we investigated the expression pattern of a newly identified circRNA (hsa_circ_0017109) in n
Externí odkaz:
https://doaj.org/article/d7495a8586614a1c8e9f8ba66ff69940
Publikováno v:
International Journal of Retina and Vitreous, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Background Familial Exudative Vitreoretinopathy (FEVR) is a hereditary disorder characterized by peripheral avascular retina with neovascularization. Although FEVR has been thoroughly described in multiple literature publications from differ
Externí odkaz:
https://doaj.org/article/3609f54e52114ca48d118d67cd2f7daa
Publikováno v:
Autoimmunity, Vol 55, Iss 3, Pp 157-167 (2022)
Background The function and pathological significance of circular RNAs (circRNAs) in autoimmune diseases, such as rheumatoid arthritis (RA), are barely known. Here, we explored the role of circ_0088036 in RA progression and its associated mechanism.
Externí odkaz:
https://doaj.org/article/25d13184373540479988324cd7fff89f
Autor:
Vincent Le, Gabrielle Abdelmessih, Wendy A. Dailey, Cecille Pinnock, Victoria Jobczyk, Revati Rashingkar, Kimberly A. Drenser, Kenneth P. Mitton
Publikováno v:
Cells, Vol 12, Iss 21, p 2579 (2023)
Familial Exudative Vitreoretinopathy (FEVR), Norrie disease, and persistent fetal vascular syndrome (PFVS) are extremely rare retinopathies that are clinically distinct but are unified by abnormal retinal endothelial cell function, and subsequent irr
Externí odkaz:
https://doaj.org/article/44991ceb75bd4bf8b93a721d0f849f71
Autor:
Handong Dan, Dongdong Wang, Zixu Huang, Qianqian Shi, Miao Zheng, Yuanyuan Xiao, Zongming Song
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Familial exudative vitreoretinopathy (FEVR) is a complex form of blindness-causing retinal degeneration. This study investigated the potential disease-causing variants in 20 Chinese families with FEVR. Methods All available family
Externí odkaz:
https://doaj.org/article/1f3a286fe4804ba984bbade54e180837
Autor:
Hongwei Gao, Hui Dong, Jiachun Zheng, Xufeng Jiang, Mingzhi Gong, Le Hu, Jinshan He, Yongxiang Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Mesenchymal stem cells (MSCs) can differentiate into diverse cell types under specific conditions. Dysfunction in the osteogenic differentiation of MSCs can result in bone metabolism-related diseases, including osteoporosis. Accum
Externí odkaz:
https://doaj.org/article/08738edc435744938eb6e78fac2a6ae1
Autor:
L. A. Katargina, V. V. Kadyshev, E. V. Denisova, E. A. Geraskina, A. V. Marakhonov, S. A. Garifullina, I. V. Zolnikova, R. A. Zinchenko
Publikováno v:
Российский офтальмологический журнал, Vol 14, Iss 4, Pp 52-59 (2022)
Familial exudative vitreoretinopathy (FEVR)is a rare genetically heterogeneous disease with multiple types of inheritance (autosomal dominant, autosomal recessive, X-linked) and widely varying clinical features. Up to 40 % of cases of FEVR are associ
Externí odkaz:
https://doaj.org/article/7ec125d1a9c5429f9e1a8da644323697