Discontinuation of Fumaric Acid Esters is Affected by Depressive Symptomatology: A Retrospective Analysis

Autor: Frederik Krefting, Stefanie Hölsken, Manfred Schedlowski, Wiebke Sondermann

Publikováno v: Acta Dermato-Venereologica, Vol 104 (2024)

Fumaric acid esters (FAEs) remain a widespread therapy option for moderate-to-severe psoriasis. However, drug survival of FAEs is limited by adverse events (AEs) or inadequate treatment response. Depressive disturbances are highly prevalent in psoria

Externí odkaz: https://doaj.org/article/48444bc1b1bb4ebe97e2cbc029c03332

Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study

Autor: Florian Anzengruber, Matthias Augustin, Marc A. Radtke, Diamant Thaci, Nikhil Yawalkar, Markus Streit, Kristian Reich, Mathias Drach, Christina Sorbe, Lars E. French, Ulrich Mrowietz, Julia-Tatjana Maul, Peter H. Itin, Alexander A. Navarini

Publikováno v: Acta Dermato-Venereologica, Vol 99, Iss 10, Pp 871-877 (2019)

Psoriasis can involve the skin, joints, nails and cardiovascular system and result in a significant impairment in quality of life. Studies have shown a lower response rate to systemic anti-psoriatic therapies in smokers, and smoking is a trigger fact

Externí odkaz: https://doaj.org/article/45c38210af8147dc9c6f635f1d76ae11

No evidence for interactions of dimethylfumarate (DMF) and its main metabolite monomethylfumarate (MMF) with human cytochrome P450 (CYP) enzymes and the P‐glycoprotein (P‐gp) drug transporter

Autor: Jordi Aubets, Josep‐Maria Jansat, Miquel Salva, Vicky M. Birks, Richard J. Cole, Jenny Lewis, Annabell Pitcher, Michael Hall

Publikováno v: Pharmacology Research & Perspectives, Vol 7, Iss 6, Pp n/a-n/a (2019)

Abstract Dimethylfumarate (DMF) has long been used as part of a fixed combination of fumaric acid esters (FAE) in some European countries and is now available as an oral monotherapy for psoriasis. The present investigation determined whether DMF and

Externí odkaz: https://doaj.org/article/4d8a32d6fa41400880f70d48dd7d15bd

Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

Autor: Stephanie Kourakis, Cara A. Timpani, Judy B. de Haan, Nuri Gueven, Dirk Fischer, Emma Rybalka

Publikováno v: Pharmaceuticals, Vol 13, Iss 10, p 306 (2020)

Fumaric acid esters (FAEs) are small molecules with anti-oxidative, anti-inflammatory and immune-modulating effects. Dimethyl fumarate (DMF) is the best characterised FAE and is approved and registered for the treatment of psoriasis and Relapsing-Rem

Externí odkaz: https://doaj.org/article/2e7350fa9ec64be49028730d3806aac5

Highlights of the updated Dutch evidence‐ and consensus‐based guideline on psoriasis 2017

Autor: Hok Bing Thio, Errol P. Prens, C. I. Busard, M. Wakkee, Ph.I. Spuls, M. de Groot, W. J. A. de Kort, Alexander Nast, L.L.A. Lecluse, P.P.M. van Lümig, G. E. van der Kraaij, Marieke M B Seyger, Stefanie Rosumeck, R.J.B. Driessen, J.M.P.A. van den Reek, S.P. Menting, S. A. Karsch, A. Jacobs, W. R. Veldkamp, Deepak M.W. Balak, Y. Chung, E.M.G.J. de Jong, O.D. van Cranenburgh, Aniek Lamberts, P. M. J. H. Kemperman

Publikováno v: The British Journal of Dermatology
van der Kraaij, G E, Balak, D M W, Busard, C I, van Cranenburgh, O D, Chung, Y, Driessen, R J B, de Groot, M, de Jong, E M G J, Kemperman, P M J H, de Kort, W J A, Karsch, S A, Lamberts, A, Lecluse, L L A, van Lümig, P P M, Menting, S P, Prens, E P, van den Reek, J M P A, Seyger, M M B, Thio, H B, Veldkamp, W R, Wakkee, M, Nast, A, Jacobs, A, Rosumeck, S & Spuls (Chair), P I 2019, ' Highlights of the updated Dutch evidence-and consensus-based guideline on psoriasis 2017 ', British Journal of Dermatology, vol. 180, no. 1, pp. 31-42 . https://doi.org/10.1111/bjd.17198
British Journal of Dermatology, 180(1), 31-42. Wiley-Blackwell
BRITISH JOURNAL OF DERMATOLOGY, 180(1), 31-42. Wiley
British Journal of Dermatology, 180, 1, pp. 31-42
British Journal of Dermatology, 180, 31-42
British journal of dermatology, 180(1), 31-42. Wiley-Blackwell
British Journal of Dermatology, 180(1), 31-42. Wiley-Blackwell Publishing Ltd

Contains fulltext : 201048.pdf (Publisher’s version ) (Open Access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfad5eac6e0bf0b0483cf67f9496f27
http://europepmc.org/articles/PMC6849803