Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer

Autor: Kuei-Yen Tsai, Yu-Jia Chang, Chien-Yu Huang, G. M. Shazzad Hossain Prince, Hsin-An Chen, Precious Takondwa Makondi, Ying-Rou Shen, Po-Li Wei

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)

Abstract Background Colorectal cancer (CRC) is highly prevalent and lethal globally, and its prognosis remains unsatisfactory. Drug resistance is regarded as the main cause of treatment failure leading to tumor recurrence and metastasis. The overexpr

Externí odkaz: https://doaj.org/article/d03ce3cc845e45ac874480d9e1a43dd0

N-linked fucosylated glycans are biomarkers for prostate cancer with a neuroendocrine and metastatic phenotype.

Autor: Ippolito JE; Washington University in St. Louis, St. Louis, Missouri, United States., Hartig JP; Medical University of South Carolina, Charleston, SC, United States., Bejar K; The University of Texas Health Science Center at San Antonio, San Antonio, United States., Nakhoul H; Washington University in St. Louis, St. Louis, Missouri, United States., Sehn JK; Saint Louis University, St. Louis, MO, United States., Weimholt C; Washington University in St. Louis, St.Louis, MO, United States., Grimsley G; Medical University of South Carolina, United States., Nunez E; Washington University in St. Louis, St. Louis, Missouri, United States., Trikalinos NA; Washington University in St. Louis, St Louis, Missouri, United States., Chatterjee D; The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Kim EH; University of Nevada Reno, United States., Mehta AS; Medical University of South Carolina, Charleston, SC, United States., Angel PM; Medical University of South Carolina, Charleston, SC, United States., Troyer DA; Eastern Virginia Medical School, Norfolk, VA, United States., Leach RJ; The University of Texas Health Science Center at San Antonio, san antonio, tx, United States., Corey E; University of Washington, SEATTLE, WA, United States., Wu JD; Northwestern University, Chicago, IL, United States., Drake RR; Medical University of South Carolina, Charleston, South Carolina, United States.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

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Anaplasma marginale Infection of Dermacentor andersoni Primary Midgut Cell Culture Is Dependent on Fucosylated Glycans

Autor: Rubikah Vimonish, Janaina Capelli-Peixoto, Wendell C. Johnson, Hala E. Hussein, Naomi S. Taus, Kelly A. Brayton, Ulrike G. Munderloh, Susan M. Noh, Massaro W. Ueti

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Tick midgut is the primary infection site required by tick-borne pathogens to initiate their development for transmission. Despite the biological significance of this organ, cell cultures derived exclusively from tick midgut tissues are unavailable a

Externí odkaz: https://doaj.org/article/8c6a6078df61499694ab5771b0576c2b