Optimization of Extended-Release ZL-004 Nanosuspensions for In Vivo Pharmacokinetic Study to Enhance Low Solubility and Compliance

Autor: Junzhe Zhu, Chengyue Guo, Ying Xu, Jiaxin Wang, Yanna Chen, Hansen Luan, Hao Wang

Publikováno v: Molecules
Molecules, Vol 24, Iss 1, p 7 (2018)
Volume 24
Issue 1

ZL-004, a promising small molecule that increases white blood cell counts, was developed for extended-release nanosuspensions to improve low solubility and compliance of patients. In vivo pharmacokinetic studies of nanosuspensions with different part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e5310791b391e96afa7b4e2a87fc98
http://europepmc.org/articles/PMC6337511

Optimization of Extended-Release ZL-004 Nanosuspensions for In Vivo Pharmacokinetic Study to Enhance Low Solubility and Compliance.

Autor: Guo C; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. chengyueguo@outlook.com., Chen Y; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. chyann72@hotmail.com., Zhu J; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. zjz.miffy@foxmail.com., Wang J; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. wangjiaxin0108@163.com., Xu Y; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. xuying0613wh@163.com., Luan H; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. luanhansen@sina.com., Wang H; National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, China. wanghao10@sinopharm.com.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2018 Dec 20; Vol. 24 (1). Date of Electronic Publication: 2018 Dec 20.