Hypofractionated Radiotherapy in Combination With Chemotherapy Improves Outcome of Patients With Esophageal Carcinoma Tracheoesophageal Groove Lymph Node Metastasis

Autor: Jian Wang, Jingping Yu, Youqin Jiang, Dong Pei, Haiwen Zhu, Jianlin Wang

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

This study investigated the efficiency and safety of hypofractionated radiotherapy (HFR) combined with paclitaxel chemotherapy for the treatment of postsurgery tracheoesophageal groove lymph node (TGLN) metastasis in patients with esophageal cancer (

Externí odkaz: https://doaj.org/article/d8b88bd46df847cdb0324e8f4da36430

Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy

Autor: Corinne Aubel, Frédérique Penault-Lorca, F. Magnier, Clémence Dubois, Emmanuelle Mounetou, Mahchid Bamdad, Fanny Martin, Pierre Daumar, Chervin Hassel, Sylvie Guerder

Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 1, p 64 (2019)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Volume 9
Issue 1

The Triple-Negative Breast Cancer subtype (TNBC) is particularly aggressive and heterogeneous. Thus, Poly-ADP-Ribose Polymerase inhibitors were developed to improve the prognosis of patients and treatment protocols are still being evaluated. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286aca83c75c3dcf54eb0950b2eb6f45
https://www.mdpi.com/2077-0383/9/1/64

Optimization of triple-negative breast cancer treatment : development of three-dimensional cell culture models, efficacy of Olaparib (anti-PARP1) in combination with radiotherapy and chemoresistance introduced by 'Multi Drug Resistance' proteins

Autor: Dubois, Clémence

Publikováno v: Cancer. Université Clermont Auvergne [2017-2020], 2018. Français. ⟨NNT : 2018CLFAS018⟩

Breast cancer is a very complex and heterogeneous disease. Among the different molecular subtypes, Triple-Negative (TN) breast cancers are particularly aggressive and of poor prognosis. TN tumours are characterized by a lack of estrogen receptors exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f457273ae80a356ce7fe1f7a4d3f9ff9
https://tel.archives-ouvertes.fr/tel-02166394/file/2018CLFAS018-DUBOIS.pdf

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Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy.

Autor: Dubois C; Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France.; Université Clermont Auvergne, Institut Universitaire de Technologie, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France., Martin F; Département de Radiothérapie, Centre Jean Perrin, F-63000 Clermont Ferrand, France., Hassel C; Centre Hospitalier Universitaire Purpan, Centre de Physiopathologie de Toulouse Purpan, INSERM, UMR 1043/CNRS UMR 5282, Antigen Presenting Cells and CD4 T cell responses, F-31024 Toulouse, France., Magnier F; Service de Physique Médicale, Centre Jean Perrin, F-63000 Clermont Ferrand, France., Daumar P; Université Clermont Auvergne, Institut Universitaire de Technologie, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France., Aubel C; Université Clermont Auvergne, Faculté de Médecine, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France., Guerder S; Centre Hospitalier Universitaire Purpan, Centre de Physiopathologie de Toulouse Purpan, INSERM, UMR 1043/CNRS UMR 5282, Antigen Presenting Cells and CD4 T cell responses, F-31024 Toulouse, France., Mounetou E; Université Clermont Auvergne, Institut Universitaire de Technologie, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France., Penault-Lorca F; Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France., Bamdad M; Université Clermont Auvergne, Institut Universitaire de Technologie, INSERM, U1240, Imagerie Moléculaire et Stratégies Théranostiques, F-63000 Clermont Ferrand, France.

Publikováno v: Journal of clinical medicine [J Clin Med] 2019 Dec 26; Vol. 9 (1). Date of Electronic Publication: 2019 Dec 26.