Zobrazeno 1 - 10
of 460
pro vyhledávání: '"foxe1"'
Autor:
Erika Urbano De Lima, Filipe Ferreira Dos Santos, Igor Campos Da Silva, Cláudio Rogério Alves De Lima, Vitoria Sousa Frutuoso, Gustavo Felisola Caso, Paloma Ramos De Oliveira, Ana Karina Bezerra, Janete Maria Cerutti, Rodrigo Esaki Tamura, Helton Estrela Ramos, Ileana Gabriela Sanchez de Rubio
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionForkhead box E1 (FOXE1) is a transcription factor with a crucial role in thyroid morphogenesis and differentiation. Promoter hypermethylation downregulates FOXE1 expression in different tumor types; nevertheless, its expression and relati
Externí odkaz:
https://doaj.org/article/831e4e1c9a314c3e9d17001bc17f6eea
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Forkhead box E1 (FOXE1), also known as thyroid transcription factor 2 (TTF-2), belongs to a large family of forkhead transcription factors. It plays important roles in embryogenesis, cell growth, and differentiation. Cancer-specific FOXE1 hy
Externí odkaz:
https://doaj.org/article/7973ebd3c7984c328a5206e403a48747
Akademický článek
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Publikováno v:
مجله دانشکده پزشکی اصفهان, Vol 41, Iss 743, Pp 1004-1010 (2023)
مقاله پژوهشیمقدمه: تقریباً 3 درصد از ژنوم انسان غنی از GC است. این نواحی اغلب در پروموتر ژنها، به ویژه ژنهای خانهدار و ژنهای سرکوبگر
Externí odkaz:
https://doaj.org/article/0750b877950b48bbb7a6916ab33e819d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Loss of the transcription factor GLI-Similar 3 (GLIS3) function causes congenital hypothyroidism (CH) in both humans and mice due to decreased expression of several thyroid hormone (TH) biosynthetic genes in thyroid follicular cel
Externí odkaz:
https://doaj.org/article/00d726bfdce14c65b8344d1a622b9f7c
Autor:
Saskia Lenggogeni Nasroen, Florence Meliawaty, Tichvy Tammama, Putri Indriani Prasdiaz, Tias Choirunnisa, Ani Melani Maskoen
Publikováno v:
Padjadjaran Journal of Dentistry, Vol 34, Iss 3, Pp 192-201 (2022)
ABSTRACT Introduction: FOXE1 rs4460498 and GSTP-1 I105V gene polymorphisms are suspected of having a role in some of the non-syndromic cleft lip and palate (NS CLP) populations worldwide. This study aims to analyze FOXE1 rs4460498 and GSTP-1 I105V p
Externí odkaz:
https://doaj.org/article/890f1ae34d864757acd7480daaa9a06d
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the disease has also become more common than previously reported, accounting for 5–1
Externí odkaz:
https://doaj.org/article/5ae6feb5bd394508b6ffaf85bb0e54b1
Autor:
Elisa Stellaria Grassi, Giuditta Rurale, Tiziana de Filippis, Davide Gentilini, Erika Carbone, Francesca Coscia, Sarah Uraghi, Martyn Bullock, Roderick J. Clifton-Bligh, Abhinav K. Gupta, Luca Persani
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionFOXE1 is required for thyroid function and its homozygous mutations cause a rare syndromic form of congenital hypothyroidism (CH). FOXE1 has a polymorphic polyalanine tract whose involvement in thyroid pathology is controversial. Starting
Externí odkaz:
https://doaj.org/article/09451781c69c48e488588594e6a31c4c
Autor:
Sophie T. Raterman, Johannes W. Von Den Hoff, Sietske Dijkstra, Cheyenne De Vriend, Tim Te Morsche, Sanne Broekman, Jan Zethof, Erik De Vrieze, Frank A. D. T. G. Wagener, Juriaan R. Metz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Mutations in the FOXE1 gene are implicated in cleft palate and thyroid dysgenesis in humans.Methods: To investigate whether zebrafish could provide meaningful insights into the etiology of developmental defects in humans related to FOXE
Externí odkaz:
https://doaj.org/article/cd69ba0d7225418db7d9b46198853552