Zobrazeno 1 - 10
of 1 727
pro vyhledávání: '"formin"'
Autor:
Hikaru Nakagawa, Yohko Kage, Ayako Miura, Hikmawan Wahyu Sulistomo, Sho Matsuyama, Yoshihiro Yamashita, Ryu Takeya
Publikováno v:
Cell Structure and Function, Vol 49, Iss 2, Pp 111-122 (2024)
The sarcomere is the contractile unit of striated muscle and is composed of actin and myosin filaments. There is increasing evidence to support that actin assembly mediated by Fhod3, a member of the formin family of proteins, is critical for sarcomer
Externí odkaz:
https://doaj.org/article/dd014e5b586f43cdb93d600c76ab2709
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The patterns of Formin B and of the Arp2/3 complex formed during mitosis were studied in a mutant of Dictyostelium discoideum that produces multinucleate cells, which divide by the ingression of unilateral cleavage furrows. During cytokinesi
Externí odkaz:
https://doaj.org/article/503e0b85e3b44f68a8d3ecf90985ed94
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151404- (2024)
While it is well-established that F-actin networks with specific organizations and dynamics are tightly regulated by distinct sets of associated actin-binding proteins (ABPs), how ABPs self-sort to particular F-actin networks remains largely unclear.
Externí odkaz:
https://doaj.org/article/a4882102b31e4b4da07c36dd9ce9f0b0
Autor:
Meng-Hao Pan, Kun-Huan Zhang, Si-Le Wu, Zhen-Nan Pan, Ming-Hong Sun, Xiao-Han Li, Jia-Qian Ju, Shi-Ming Luo, Xiang-Hong Ou, Shao-Chen Sun
Publikováno v:
eLife, Vol 12 (2024)
During mammalian oocyte meiosis, spindle migration and asymmetric cytokinesis are unique steps for the successful polar body extrusion. The asymmetry defects of oocytes will lead to the failure of fertilization and embryo implantation. In present stu
Externí odkaz:
https://doaj.org/article/094ca04db43c4aa194da6a073507a91f
Autor:
David Micinski, Pirta Hotulainen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The location of the axon initial segment (AIS) at the junction between the soma and axon of neurons makes it instrumental in maintaining neural polarity and as the site for action potential generation. The AIS is also capable of large-scale relocatio
Externí odkaz:
https://doaj.org/article/1b52bd2298284a81bcf0881447b9541a
Helical motors and formins synergize to compact chiral filopodial bundles: A theoretical perspective
Autor:
Ondrej Maxian, Alex Mogilner
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 1, Pp 151383- (2024)
Chiral actin bundles have been shown to play an important role in cell dynamics, but our understanding of the molecular mechanisms which combine to generate chirality remains incomplete. To address this, we numerically simulate a crosslinked filopodi
Externí odkaz:
https://doaj.org/article/c07d22d819fc4d1588edd64633b5bf6d
Autor:
Georges Chehade, Nady El Hajj, Mohamed Aittaleb, Maisa I. Alkailani, Yosra Bejaoui, Asma Mahdi, Arwa A. H. Aldaalis, Michael Verbiest, Julie Lelotte, Nuria Ruiz-Reig, Irene Durá, Christian Raftopoulos, Nicolas Tajeddine, Fadel Tissir
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundGlioblastoma is one of the most aggressive primary brain tumors, with a poor outcome despite multimodal treatment. Methylation of the MGMT promoter, which predicts the response to temozolomide, is a well-established prognostic marker for gl
Externí odkaz:
https://doaj.org/article/1369f93b831e4ee098f1f9224cf0cca6
Autor:
Andrew T. Phillips, Edward F. Boumil, Arunkumar Venkatesan, Christine Tilstra-Smith, Nileyma Castro, Barry E. Knox, Jessica L. Henty-Ridilla, Audrey M. Bernstein
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151347- (2023)
The differentiation of fibroblasts into pathological myofibroblasts during wound healing is characterized by increased cell surface expression of αv-integrins. Our previous studies found that the deubiquitinase (DUB) USP10 removes ubiquitin from αv
Externí odkaz:
https://doaj.org/article/a52d26fda8504051aa4f98b7a83e4896
Publikováno v:
Nucleus, Vol 13, Iss 1, Pp 35-48 (2022)
There is growing appreciation that architectural components of the nucleus regulate gene accessibility by altering chromatin organization. While nuclear membrane connector proteins link the mechanosensitive actin cytoskeleton to the nucleoskeleton, a
Externí odkaz:
https://doaj.org/article/90c25eff0d8a4ad19afa374dfd47e733
Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 8285-8298 (2022)
Qinglin Zhang,* He Nie,* Jiadong Pan, Haoran Xu, Qiang Zhan Department of Gastroenterology, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214023, People’s Republic of China*These authors contribut
Externí odkaz:
https://doaj.org/article/c45a9de12d2149d4a132ea7c906969c6