Zobrazeno 1 - 10
of 3 132
pro vyhledávání: '"for the Alzheimer’s Disease Neuroimaging Initiative"'
Autor:
Jiaxuan Peng, Guangying Zheng, Mengmeng Hu, Zihan Zhang, Zhongyu Yuan, Yuyun Xu, Yuan Shao, Yang Zhang, Xiaojun Sun, Lu Han, Xiaokai Gu, Zhenyu Shu, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective To identify white matter fiber injury and network changes that may lead to mild cognitive impairment (MCI) progression, then a joint model was constructed based on neuropsychological scales to predict high-risk individuals for Alzh
Externí odkaz:
https://doaj.org/article/c29530e06b984735b456bb7abd2605d0
Autor:
Jiaxin Li, Yueqin Hu, Yunzhi Xu, Xue Feng, Craig H. Meyer, Weiying Dai, Li Zhao, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background The cerebrospinal fluid (CSF), primarily generated by the choroid plexus (ChP), is the major carrier of the glymphatic system. The alternations of CSF production and the ChP can be associated with the Alzheimer’s disease (AD). T
Externí odkaz:
https://doaj.org/article/2714382bb56c475a9a8b0c9c3d4ece65
Autor:
Rory Boyle, Diana L. Townsend, Hannah M. Klinger, Catherine E. Scanlon, Ziwen Yuan, Gillian T. Coughlan, Mabel Seto, Zahra Shirzadi, Wai-Ying Wendy Yau, Roos J. Jutten, Christoph Schneider, Michelle E. Farrell, Bernard J. Hanseeuw, Elizabeth C. Mormino, Hyun-Sik Yang, Kathryn V. Papp, Rebecca E. Amariglio, Heidi I. L. Jacobs, Julie C. Price, Jasmeer P. Chhatwal, Aaron P. Schultz, Michael J. Properzi, Dorene M. Rentz, Keith A. Johnson, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Leveraging Alzheimer’s disease (AD) imaging biomarkers and longitudinal cognitive data may allow us to establish evidence of cognitive resilience (CR) to AD pathology in-vivo. Here, we applied latent class mixture modeling, adju
Externí odkaz:
https://doaj.org/article/533e6b89a4fd4deeb58b8bf4d29de93c
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Melanie A. Dratva, Sarah J. Banks, Matthew S. Panizzon, Douglas Galasko, Erin E. Sundermann, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Past research suggests that low testosterone levels relate to poorer cognitive function and higher Alzheimer’s disease (AD) risk; however, these findings are inconsistent and are mostly derived from male samples, despite similar
Externí odkaz:
https://doaj.org/article/fcde095906224ad89d8cee2f09132007
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss S1, Pp 1-14 (2024)
Abstract Background Alzheimer’s Disease (AD) is a progressive memory disorder that causes irreversible cognitive decline. Given that there is currently no cure, it is critical to detect AD in its early stage during the disease progression. Recently
Externí odkaz:
https://doaj.org/article/d30cd7da0cfa4c6b81aeda9f2bc608b5
Autor:
Tovia Jacobs, Sean R. Jacobson, Juan Fortea, Jeffrey S. Berger, Alok Vedvyas, Karyn Marsh, Tianshe He, Eugenio Gutierrez-Jimenez, Nathanael R. Fillmore, Moses Gonzalez, Luisa Figueredo, Naomi L. Gaggi, Chelsea Reichert Plaska, Nunzio Pomara, Esther Blessing, Rebecca Betensky, Henry Rusinek, Henrik Zetterberg, Kaj Blennow, Lidia Glodzik, Thomas M. Wisniweski, Mony J. de Leon, Ricardo S. Osorio, Jaime Ramos-Cejudo, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background An elevated neutrophil–lymphocyte ratio (NLR) in blood has been associated with Alzheimer’s disease (AD). However, an elevated NLR has also been implicated in many other conditions that are risk factors for AD, prompting inves
Externí odkaz:
https://doaj.org/article/64735eb95a84489b999f38452eb3aac9
Autor:
Anna Marier, Mahsa Dadar, Florence Bouhali, Maxime Montembeault, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Irregular word reading has been used to estimate premorbid intelligence in Alzheimer’s disease (AD) dementia. However, reading models highlight the core influence of semantic abilities on irregular word reading, which shows earl
Externí odkaz:
https://doaj.org/article/d11f6c86f8a34e81bf990ee0560fe5f5
Impact of amyloid and tau positivity on longitudinal brain atrophy in cognitively normal individuals
Autor:
Motonobu Fujishima, Yohei Kawasaki, Toshiharu Mitsuhashi, Hiroshi Matsuda, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Individuals on the preclinical Alzheimer's continuum, particularly those with both amyloid and tau positivity (A + T +), display a rapid cognitive decline and elevated disease progression risk. However, limited studies exist on br
Externí odkaz:
https://doaj.org/article/9d39a277822943c68dac2b006216f443
Autor:
Chen Xue, Darui Zheng, Yiming Ruan, Wenxuan Guo, Jun Hu, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundStable mild cognitive impairment (sMCI) and progressive mild cognitive impairment (pMCI) represent two distinct subtypes of mild cognitive impairment (MCI). Early and effective diagnosis and accurate differentiation between sMCI and pMCI ar
Externí odkaz:
https://doaj.org/article/505e16cb2cbd48ab93599f30f48b0e16