Zobrazeno 1 - 10
of 3 418
pro vyhledávání: '"for the Alzheimer's Disease Neuroimaging In"'
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Sylvain Lehmann, Susanna Schraen-Maschke, Luc Buée, Jean-Sébastien Vidal, Constance Delaby, Christophe Hirtz, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Olivier Hanon, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Current AT(N) stratification for Alzheimer’s disease (AD) accounts for complex combinations of amyloid (A), tau proteinopathy (T) and neurodegeneration (N) signatures. Understanding the transition between these different stages
Externí odkaz:
https://doaj.org/article/c860af25033746cb82e1ae7cdbcb2d80
Autor:
Emma M. Tinney, Goretti España‐Irla, Aaron E.L. Warren, Lauren N. Whitehurst, Alexandra M Stillman, Charles H. Hillman, Timothy P. Morris, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 9, Pp 2314-2326 (2024)
Abstract Objectives Traumatic brain injury (TBI) is associated with sleep deficits, but it is not clear why some report sleep disturbances and others do not. The objective of this study was to assess the associations between axonal injury, sleep, and
Externí odkaz:
https://doaj.org/article/e6f9d1e8282e41c18e0131e597f1554a
Autor:
Tim M. Emmenegger, Raoul Seiler, Paul G. Unschuld, Patrick Freund, Jan Klohs, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Alzheimer’s disease (AD) is characterized by progressive episodic memory dysfunction. A prominent hallmark of AD is gradual brain atrophy. Despite extensive research on brain pathology, the understanding of spinal cord pathology in AD and
Externí odkaz:
https://doaj.org/article/b0e4a03e3de04c5282b86746aa12b0b1
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Introduction Sleep disorders, particularly insomnia and obstructive sleep apnea, are associated with dyslipidemia in the general population. The study’s aim was to explore the association between pathological Cholesterol and Triglyceride l
Externí odkaz:
https://doaj.org/article/6753176fe9c34c9a8f7eac80d3a110a2
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Plasma neurofilament light chain (NfL) is a blood biomarker of neurodegeneration, including Alzheimer’s disease. However, its usefulness may be influenced by common conditions in older adults, including amyloid-β (Aβ) depositi
Externí odkaz:
https://doaj.org/article/e55c5cab7e454f1281fbeb8380958992
Autor:
Jiaxuan Peng, Guangying Zheng, Mengmeng Hu, Zihan Zhang, Zhongyu Yuan, Yuyun Xu, Yuan Shao, Yang Zhang, Xiaojun Sun, Lu Han, Xiaokai Gu, Zhenyu Shu, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective To identify white matter fiber injury and network changes that may lead to mild cognitive impairment (MCI) progression, then a joint model was constructed based on neuropsychological scales to predict high-risk individuals for Alzh
Externí odkaz:
https://doaj.org/article/c29530e06b984735b456bb7abd2605d0
Autor:
Krishnakumar Vaithianathan, Julian Benadit Pernabas, Latha Parthiban, Mamoon Rashid, Sultan S. Alshamrani, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PeerJ Computer Science, Vol 10, p e2502 (2024)
Several deep learning networks are developed to identify the complex atrophic patterns of Alzheimer's disease (AD). Among various activation functions used in deep neural networks, the rectifier linear unit is the most used one. Even though these fun
Externí odkaz:
https://doaj.org/article/65579e6e8cd0481eb18f1ddf8088ba08
Autor:
Jiaxin Li, Yueqin Hu, Yunzhi Xu, Xue Feng, Craig H. Meyer, Weiying Dai, Li Zhao, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background The cerebrospinal fluid (CSF), primarily generated by the choroid plexus (ChP), is the major carrier of the glymphatic system. The alternations of CSF production and the ChP can be associated with the Alzheimer’s disease (AD). T
Externí odkaz:
https://doaj.org/article/2714382bb56c475a9a8b0c9c3d4ece65
Autor:
Rory Boyle, Diana L. Townsend, Hannah M. Klinger, Catherine E. Scanlon, Ziwen Yuan, Gillian T. Coughlan, Mabel Seto, Zahra Shirzadi, Wai-Ying Wendy Yau, Roos J. Jutten, Christoph Schneider, Michelle E. Farrell, Bernard J. Hanseeuw, Elizabeth C. Mormino, Hyun-Sik Yang, Kathryn V. Papp, Rebecca E. Amariglio, Heidi I. L. Jacobs, Julie C. Price, Jasmeer P. Chhatwal, Aaron P. Schultz, Michael J. Properzi, Dorene M. Rentz, Keith A. Johnson, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Leveraging Alzheimer’s disease (AD) imaging biomarkers and longitudinal cognitive data may allow us to establish evidence of cognitive resilience (CR) to AD pathology in-vivo. Here, we applied latent class mixture modeling, adju
Externí odkaz:
https://doaj.org/article/533e6b89a4fd4deeb58b8bf4d29de93c