Zobrazeno 1 - 10
of 158
pro vyhledávání: '"folate receptor beta"'
Autor:
Fenghua Zhang, Bo Huang, Sagar M. Utturkar, Weichuan Luo, Gregory Cresswell, Seth A. Herr, Suilan Zheng, John V. Napoleon, Rina Jiang, Boning Zhang, Muyi Liu, Nadia Lanman, Madduri Srinivasarao, Timothy L. Ratliff, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Folate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and myeloid-deri
Externí odkaz:
https://doaj.org/article/6dc8dbece4744d66b4109cdad3fb1700
Autor:
Maarten M. Steinz, Aiarpi Ezdoglian, Fatemeh Khodadust, Carla F. M. Molthoff, Madduri Srinivasarao, Philip S. Low, Gerben J. C. Zwezerijnen, Maqsood Yaqub, Wissam Beaino, Albert D. Windhorst, Sander W. Tas, Gerrit Jansen, Conny J. van der Laken
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Non-invasive imaging modalities constitute an increasingly important tool in diagnostic and therapy response monitoring of patients with autoimmune diseases, including rheumatoid arthritis (RA). In particular, macrophage imaging with positron emissio
Externí odkaz:
https://doaj.org/article/029857162ef5491a9e59a32e5a1d6081
Autor:
Yingjuan J. Lu, Leroy W. Wheeler, II, Haiyan Chu, Paul J. Kleindl, Michael Pugh, Fei You, Satish Rao, Gabriela Garcia, Henry Y. Wu, Andre P. da Cunha, Richard Johnson, Elaine Westrick, Vicky Cross, Alex Lloyd, Christina Dircksen, Patrick J. Klein, Iontcho R. Vlahov, Philip S. Low, Christopher P. Leamon
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422- (2021)
Summary: Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar aff
Externí odkaz:
https://doaj.org/article/e2fda03da1f14baea081c09735a4dc68
Autor:
Yingwen Hu, Bingbing Wang, Jiayin Shen, Stewart A. Low, Karson S. Putt, Hans W. M. Niessen, Eric L. Matteson, Linda Murphy, Clemens Ruppert, Gerrit Jansen, Stephen J. Oliver, Yang Feng, Dimiter S. Dimitrov, Cheryl Nickerson-Nutter, Philip S. Low
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Objectives Most therapies for autoimmune and inflammatory diseases either neutralize or suppress production of inflammatory cytokines produced by activated macrophages (e.g., TNFα, IL-1, IL-6, IL-17, GM-CSF). However, no approved therapies
Externí odkaz:
https://doaj.org/article/1dc2d4681dd3423db7d7c71fbd322d51
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Akademický článek
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Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 238 (2020)
Herein, we discuss the potential role of folic acid-based radiopharmaceuticals for macrophage imaging to support clinical decision-making in patients with COVID-19. Activated macrophages play an important role during coronavirus infections. Exuberant
Externí odkaz:
https://doaj.org/article/29ba9d1b008f48d3ae67411db9e1adb0
Autor:
Seung-Hae Kwon, Ruda Lee, Yong Il Park, Gibok Lee, Minwoo Kim, Jung Hoon Choi, Min Lin, Keiichi Motoyama, Takuro Niidome
Publikováno v:
Journal of Controlled Release. 330:1-14
Non-small cell lung cancer (NSCLC) is the leading cause of lung cancer-related deaths worldwide. Tumor-associated macrophages (TAMs), which can be polarized into tumor-promoting M2 phenotype, overexpress folate receptor beta (FRβ) and are associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4f4d5dfb73214a4aac3b311a20ad6e
https://doi.org/10.1016/j.jconrel.2020.12.011
https://doi.org/10.1016/j.jconrel.2020.12.011
Autor:
Philip S. Low, Paul J. Kleindl, Andre P. da Cunha, Satish Rao, Patrick J. Klein, Leroy W Wheeler, Henry Y. Wu, Christopher P. Leamon, Yingjuan J. Lu, Fei You, Alex Lloyd, Christina Dircksen, Chu Haiyan, Michael Pugh, Gabriela E. Garcia, Vicky Cross, Elaine Westrick, Richard J. Johnson, Iontcho R. Vlahov
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff3f0adb683c62473135f1023e5e206
http://www.sciencedirect.com/science/article/pii/S2666379121002846
http://www.sciencedirect.com/science/article/pii/S2666379121002846
Akademický článek
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