Zobrazeno 1 - 10
of 293
pro vyhledávání: '"folate cycle"'
Publikováno v:
Medičnì Perspektivi, Vol 29, Iss 3, Pp 4-11 (2024)
Enzymes of the folate cycle participate in the process of remethylation of homocysteine (HC) to methionine, where folates are coenzymes for methyl transfer. The aim of the work was to identify the interrelationships of gene polymorphisms of associati
Externí odkaz:
https://doaj.org/article/740ee36503634e2785730b5fdaeba649
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 8, Pp 1011-1022 (2024)
Objective·To explore the regulatory mechanism of folate cycle metabolism in the immunosuppressive effect of myeloid derived suppressor cells (MDSCs).Methods·Bone marrow cells were isolated from C57BL/6 mice and cultured in RPMI 1640 medium suppleme
Externí odkaz:
https://doaj.org/article/2e308de0f5314719b6b598675528efba
Publikováno v:
Medičnì Perspektivi, Vol 29, Iss 2, Pp 229-236 (2024)
Funicular myelosis (subacute combined degeneration) is a disease characterized by the development of degeneration of the posterior and lateral cords of the spinal cord. Funicular myelosis is a neurological complication of vitamin B12 deficiency, wh
Externí odkaz:
https://doaj.org/article/eea3702a376a410994bf377e7424556c
Autor:
Christine L. Miller
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 4, Iss 3, Pp 198-239 (2024)
Transmethylation in the context of psychiatry has historically referred to the enzymatic transfer of a methyl group from one biochemical to another, whose resulting function can change so dramatically that a biochemical like tryptamine, for example,
Externí odkaz:
https://doaj.org/article/4677a03f13ba49bb88f3015ac5e30f23
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background The folate cycle of one-carbon (C1) metabolism, which plays a central role in the biosynthesis of nucleotides and amino acids, demonstrates the significance of metabolic adaptation. We investigated the evolutionary history of the
Externí odkaz:
https://doaj.org/article/96d46baf09ee45ec82364357fb137864
Autor:
Yu. N. Reshetnikova, I. V. Ponomarenko, V. М. Churnosov, M. S. Ponomarenko, M. I. Churnosov, E. A. Reshetnikov
Publikováno v:
Акушерство, гинекология и репродукция, Vol 18, Iss 1, Pp 46-54 (2024)
Aim: to assess associations between folate cycle gene polymorphism and neonatal birth weight in pregnant women with fetal growth retardation (FGR) and related functional effects in population of the Central Black Earth Region.Materials and Methods. 9
Externí odkaz:
https://doaj.org/article/f72c542212434a8f9a74c8a5b01f9dd3
Autor:
V. O. Bitsadze, E. V. Slukhanchuk, A. G. Solopova, J. Kh. Khizroeva, D. V. Shcherbakov, F. E. Yakubova, J.-C. Gris, I. Elalamy, N. D. Degtyareva, A. V. Lazarchuk, M. A. Gileva, N. V. Samburova, Z. D. Aslanova, D. V. Blinov, A. S. Shkoda, A. D. Makatsariya
Publikováno v:
Акушерство, гинекология и репродукция, Vol 17, Iss 4, Pp 390-401 (2023)
Introduction. Hyperhomocysteinemia (HHC) is one of the arms in the pathogenesis of thrombotic complications in female cancer patients.Aim: to assess an HHC-related impact to developing thrombotic complications in patients with malignant neoplasms of
Externí odkaz:
https://doaj.org/article/32e255c118c14182b2c2b8e94495896d
Autor:
Ana Filipa Sobral, Andrea Cunha, Vera Silva, Eva Gil-Martins, Renata Silva, Daniel José Barbosa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9339 (2024)
Cellular metabolism is crucial for various physiological processes, with folate-dependent one-carbon (1C) metabolism playing a pivotal role. Folate, a B vitamin, is a key cofactor in this pathway, supporting DNA synthesis, methylation processes, and
Externí odkaz:
https://doaj.org/article/4218230dd58d427ca4185d9c8bbbfd87
Publikováno v:
Journal of Marine Science and Engineering, Vol 12, Iss 5, p 786 (2024)
Folate, also known as vitamin B9, plays a crucial role in the one-carbon (1C) metabolism, a conserved pathway from microbes to humans. The 1C metabolism, consisting of the folate and methionine cycles, is essential in many biological processes such a
Externí odkaz:
https://doaj.org/article/2f4fe1070f3844c3a1149c756639867d
Publikováno v:
Journal of Ophthalmology, Iss 5, Pp 3-11 (2022)
Background: Hyperhomocysteinemia is important in the development of endothelial dysfunction, a pathogenetic component of diabetic retinopathy (DR) in type 2 diabetes mellitus (DM2). The major cause of homocysteine accumulation is missing or dysfuncti
Externí odkaz:
https://doaj.org/article/6a3c21b0e01d49f198e07e4d2be669dd