Ultra Stable Molecular Sensors by Submicron Referencing and Why They Should Be Interrogated by Optical Diffraction—Part II. Experimental Demonstration

Autor: Andreas Frutiger, Karl Gatterdam, Yves Blickenstorfer, Andreas Michael Reichmuth, Christof Fattinger, János Vörös

Publikováno v: Sensors, Vol 21, Iss 1, p 9 (2020)

Label-free optical biosensors are an invaluable tool for molecular interaction analysis. Over the past 30 years, refractometric biosensors and, in particular, surface plasmon resonance have matured to the de facto standard of this field despite a sig

Externí odkaz: https://doaj.org/article/71bfb78fff76414c83391bb1ef86784b

Investigating Complex Samples with Molograms of Low-Affinity Binders

Autor: Fridolin Treindl, Andreas M. Reichmuth, Katharina Kübrich, Janos Vörös, Dmitry Momotenko, Andreas Frutiger, Christof Fattinger, Yves Blickenstorfer, Volker Gatterdam

Publikováno v: ACS Sensors, 6 (3)

In vitro diagnostics relies on the quantification of minute amounts of a specific biomolecule, called biomarker, from a biological sample. The majority of clinically relevant biomarkers for conditions beyond infectious diseases are detected by means

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae0a872da6760edb8d7ce0efadc4d20

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Ultra Stable Molecular Sensors by Submicron Referencing and Why They Should Be Interrogated by Optical Diffraction-Part II. Experimental Demonstration.

Autor: Frutiger A; Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, University and ETH Zürich, 8092 Zürich, Switzerland., Gatterdam K; Institute of Structural Biology, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany., Blickenstorfer Y; Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, University and ETH Zürich, 8092 Zürich, Switzerland., Reichmuth AM; Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, University and ETH Zürich, 8092 Zürich, Switzerland., Fattinger C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, 4070 Basel, Switzerland., Vörös J; Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, University and ETH Zürich, 8092 Zürich, Switzerland.

Publikováno v: Sensors (Basel, Switzerland) [Sensors (Basel)] 2020 Dec 22; Vol. 21 (1). Date of Electronic Publication: 2020 Dec 22.