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Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models.

Autor: Park YJ; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Program in Development, Disease Models & Therapeutics, Baylor College of Medicine, Houston, TX 77030, USA., Lu TC; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Jackson T; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Program in Cancer Cell Biology, Baylor College of Medicine, Houston, TX 77030, USA., Goodman LD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Ran L; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Chen J; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Liang CY; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan., Harrison E; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Ko C; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Hsu AL; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan, Ann Arbor, MI 28109, USA., Yamamoto S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Program in Development, Disease Models & Therapeutics, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA., Qi Y; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Bellen HJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Program in Development, Disease Models & Therapeutics, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA., Li H; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 13. Date of Electronic Publication: 2024 Mar 13.

Exploring the Efficient Natural Products for the Therapy of Parkinson's Disease via Drosophila Melanogaster (Fruit Fly) Models.

Autor: Zhang W; School of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China., Ju Y; School of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China., Ren Y; School of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China., Miao Y; Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, 300250, Tianjin, China., Wang Y; School of Pharmaceutical Science and Technology, Tianjin University, 300072, Tianjin, China.

Publikováno v: Current drug targets [Curr Drug Targets] 2024; Vol. 25 (2), pp. 77-93.