Zobrazeno 1 - 10
of 4 629
pro vyhledávání: '"flux balance analysis"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 4, Pp 861-870 (2024)
Saccharomyces cerevisiae, a widely utilized model organism, has seen continuous updates to its genome-scale metabolic model (GEM) to enhance the prediction performance for metabolic engineering and systems biology. This study presents an auxotrophy-b
Externí odkaz:
https://doaj.org/article/796f6ddd73124aaf9b9db8ee37ea9b28
Publikováno v:
mSystems, Vol 9, Iss 11 (2024)
ABSTRACT Photorhabdus is a bacterial genus containing both insect and emerging human pathogens. Most insect-restricted species display temperature restriction, unable to grow above 34°C, while Photorhabdus asymbiotica can grow at 37°C to infect mam
Externí odkaz:
https://doaj.org/article/0a95af45a2954883ac91c76c21fd743c
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Aspergillus tubingensis is a citric acid-producing fungus that can utilize sugars in hydrolysate of lignocellulosic biomass such as sugarcane bagasse and, unlike A. niger, does not produce mycotoxins. To date, no attempt has been
Externí odkaz:
https://doaj.org/article/a604f0b433b3487698f0678fb7d7f05a
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 1, Pp 33-42 (2024)
Metabolic modeling and machine learning (ML) are crucial components of the evolving next-generation tools in systems and synthetic biology, aiming to unravel the intricate relationship between genotype, phenotype, and the environment. Nonetheless, th
Externí odkaz:
https://doaj.org/article/336fa4e2a8254caf956c0bfea2910a81
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Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Mechanistic, constraint-based models of microbial isolates or communities are a staple in the metabolic analysis toolbox, but predictions about microbe-microbe and microbe-environment interactions are only as good as the accuracy of transporter annot
Externí odkaz:
https://doaj.org/article/3d84aa9ed820429e823627cd7de03023
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Cystic fibrosis (CF), an inherited genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene, results in sticky and thick mucosal fluids. This environment facilitates the colonization of various mic
Externí odkaz:
https://doaj.org/article/d04d9a88b23d4e7eaea4c85ab362a6b5
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background Given a genome-scale metabolic model (GEM) of a microorganism and criteria for optimization, flux balance analysis (FBA) predicts the optimal growth rate and its corresponding flux distribution for a specific medium. FBA has been
Externí odkaz:
https://doaj.org/article/c675c3a1e26d48dc941d21594b0f6b73
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Pseudomonas putida S12 is a gram-negative bacterium renowned for its high tolerance to organic solvents and metabolic versatility, making it attractive for various applications, including bioremediation and the production of aroma
Externí odkaz:
https://doaj.org/article/b330c1218bac4f7eb28cd34b4c2ea265
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background Flux Balance Analysis (FBA) is a key metabolic modeling method used to simulate cellular metabolism under steady-state conditions. Its simplicity and versatility have led to various strategies incorporating transcriptomic and prot
Externí odkaz:
https://doaj.org/article/61ff3d2e01774e70a31fa45c14249195