Zobrazeno 1 - 10
of 182
pro vyhledávání: '"flightless I"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Surgical repair of tendons is common, but function is often limited due to the formation of flexor tendon adhesions which reduce the mobility and use of the affected digit and hand. The severity of adhesion formation is dependent
Externí odkaz:
https://doaj.org/article/1bd42acf65aa45c5983b52d3ed74d363
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Healing of tendons after injury involves the proliferation of tenocytes and the production of extracellular matrix; however, their capacity to heal is limited by poor cell density and limited growth factor activity. Flightless I (
Externí odkaz:
https://doaj.org/article/564e55e2f15f4eb69f4022bb07c9462b
Autor:
Stuart J. Mills, Parinaz Ahangar, Hannah M. Thomas, Benjamin R. Hofma, Rachael Z. Murray, Allison J. Cowin
Publikováno v:
Cells, Vol 11, Iss 14, p 2192 (2022)
TLR4 plays a pivotal role in orchestrating inflammation and tissue repair. Its expression has finally been balanced to initiate the early, robust immune response necessary for efficient repair without excessively amplifying and prolonging inflammatio
Externí odkaz:
https://doaj.org/article/6f9689ebf2094fe39c1414fa33c01886
Autor:
Xanthe L. Strudwick, Allison J. Cowin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Flightless I is an actin-binding member of the gelsolin family of actin-remodeling proteins that inhibits actin polymerization but does not possess actin severing ability. Flightless I functions as a regulator of many cellular processes including pro
Externí odkaz:
https://doaj.org/article/210d0a47b70e41c4b81355c532b2e857
Autor:
Réka Pintér, Tamás Huber, Péter Bukovics, Péter Gaszler, Andrea Teréz Vig, Mónika Ágnes Tóth, Gabriella Gazsó-Gerhát, Dávid Farkas, Ede Migh, József Mihály, Beáta Bugyi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Flightless-I is a unique member of the gelsolin superfamily alloying six gelsolin homology domains and leucine-rich repeats. Flightless-I is an established regulator of the actin cytoskeleton, however, its biochemical activities in actin dynamics are
Externí odkaz:
https://doaj.org/article/01dcf85053a84e5eb080d07e1355812f
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease characterized by excessive inflammation and disrupted skin barrier function. Although the etiology of AD is not completely understood, clinical and basic studies suggest increasin
Externí odkaz:
https://doaj.org/article/1cb9450eb5cc4c2ab61bfe3aec381e26
Autor:
Allison J. Cowin, Xanthe L. Strudwick
Publikováno v:
Cells, Vol 1, Iss 4, Pp 1313-1327 (2012)
Wound healing results in the repair of injured tissues however fibrosis and scar formation are, more often than not the unfortunate consequence of this process. The ability of lower order vertebrates and invertebrates to regenerate limbs and tissues
Externí odkaz:
https://doaj.org/article/a94b192471f44510bd2b7f794134211f
Akademický článek
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