Zobrazeno 1 - 10
of 191
pro vyhledávání: '"filomena de nigris"'
Autor:
Maria Consiglia Trotta, Carlo Gesualdo, Caterina Claudia Lepre, Marina Russo, Franca Ferraraccio, Iacopo Panarese, Ernesto Marano, Paolo Grieco, Francesco Petrillo, Anca Hermenean, Francesca Simonelli, Michele D’Amico, Claudio Bucolo, Francesca Lazzara, Filomena De Nigris, Settimio Rossi, Chiara Bianca Maria Platania
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction:The purine analog 6-thioguanine (6TG), an old drug approved in the 60s to treat acute myeloid leukemia (AML), was tested in the diabetic retinopathy (DR) experimental in vivo setting along with a molecular modeling approach.Methods:A com
Externí odkaz:
https://doaj.org/article/ce3089b4c44f4ef1bee2c74f13fa2c5b
Autor:
Christofer Rupert, Carmela Dell’ Aversana, Laura Mosca, Vittorino Montanaro, Davide Arcaniolo, Marco De Sio, Antonio Bilancio, Lucia Altucci, Wulf Palinski, Roberto Pili, Filomena de Nigris
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. Large-scale metabolomic data have associated metabolic alterations with the pathogenesis and progression of renal carcinoma and have correlated mi
Externí odkaz:
https://doaj.org/article/74f93420daa1482c9b13b147589ffd31
Autor:
Concetta Meo, Giuseppe Palma, Francesca Bruzzese, Alfredo Budillon, Claudio Napoli, Filomena de Nigris
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Early in the COVID-19 pandemic, it emerged that the risk of severe outcomes was greater in patients with co-morbidities, including cancer. The huge effort undertaken to fight the pandemic, affects the management of cancer care, influencing t
Externí odkaz:
https://doaj.org/article/692b51aa054246c299fee39169d6aa80
Publikováno v:
Cells, Vol 12, Iss 17, p 2204 (2023)
Genomic-based precision medicine has not only improved tumour therapy but has also shown its weaknesses. Genomic profiling and mutation analysis have identified alterations that play a major role in sarcoma pathogenesis and evolution. However, they h
Externí odkaz:
https://doaj.org/article/d5a7f8dd3c5a4578b414ec2834b18410
Autor:
Wulf Palinski, Maria Monti, Rosa Camerlingo, Ilaria Iacobucci, Serena Bocella, Federica Pinto, Clara Iannuzzi, Gelsomina Mansueto, Sara Pignatiello, Flavio Fazioli, Michele Gallo, Laura Marra, Flora Cozzolino, Annarosaria De Chiara, Piero Pucci, Antonio Bilancio, Filomena de Nigris
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-13 (2021)
Abstract The tumor microenvironment modulates cancer growth. Extracellular vesicles (EVs) have been identified as key mediators of intercellular communication, but their role in tumor growth is largely unexplored. Here, we demonstrate that EVs from s
Externí odkaz:
https://doaj.org/article/02c6adb836e64395ace05f242ac52a2b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7509 (2023)
Both progression from the early pathogenic events to clinically manifest cardiovascular diseases (CVD) and cancer impact the integrity of the vascular system. Pathological vascular modifications are affected by interplay between endothelial cells and
Externí odkaz:
https://doaj.org/article/0c9dd32db9ac44d781ca5e0f91dc8be1
Autor:
Edoardo Tacconi, Giuseppe Palma, Davide De Biase, Antonio Luciano, Massimiliano Barbieri, Filomena de Nigris, Francesca Bruzzese
Publikováno v:
Nutrients, Vol 15, Iss 3, p 563 (2023)
Trimethylamine N-oxide (TMAO) is a microbial metabolite derived from nutrients, such as choline, L-carnitine, ergothioneine and betaine. Recently, it has come under the spotlight for its close interactions with gut microbiota and implications for gas
Externí odkaz:
https://doaj.org/article/b5065a64446d4c5c86905f1e43573141
Autor:
Silvia Nuzzo, Silvia Catuogno, Maria Capuozzo, Alfonso Fiorelli, Piotr Swiderski, Serena Boccella, Filomena de Nigris, Carla Lucia Esposito
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 256-263 (2019)
Non-small-cell lung cancer (NSCLC) accounts for 85%–90% of all cases of lung cancer that is the most deadly type of cancer. Despite advances in chemotherapy and radiotherapy, severe side effects and frequent drug resistance limit the success of the
Externí odkaz:
https://doaj.org/article/a85c657154e04d3d8811c3e693d25318
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Neuroendocrine tumors, or NETs, are cancer originating in neuroendocrine cells. They are mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by signs and symptoms caused by the oversecretion of hormones and other su
Externí odkaz:
https://doaj.org/article/7cac5d7bcce44e1e871112be8713727e
Autor:
Carla Lucia Esposito, Silvia Nuzzo, Silvia Catuogno, Simona Romano, Filomena de Nigris, Vittorio de Franciscis
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 398-411 (2018)
Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor in adults, and despite advances in neuro-oncology, the prognosis for patients remains dismal. The signal transducer and activator of transcription-3 (STAT3) has been reported
Externí odkaz:
https://doaj.org/article/4282b9f693a6471598054e72cc554a78